{"id":"W2162109316","doi":"10.1016/j.cell.2013.01.008","title":"The Dynamic Process of β2-Adrenergic Receptor Activation","year":2013,"lang":"en","type":"article","venue":"Cell","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":809,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences","keywords":"Biology; Process (computing); Receptor; Adrenergic receptor; Cell biology; Computational biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003630666,0.0002411873,0.0003760871,0.000510008,0.0003998299,0.001718346,0.0005287295,0.00053171,0.0018825],"category_scores_gemma":[0.0004455946,0.0003545223,0.0002235448,0.0003942224,0.0005472385,0.002008641,0.0005637503,0.001023912,0.0008530904],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006571524,"about_ca_system_score_gemma":0.0003291144,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004039289,"about_ca_topic_score_gemma":0.0004729676,"domain_scores_codex":[0.9997,0.00003402917,0.00001110421,0.00007013966,0.0001326371,0.00005219151],"domain_scores_gemma":[0.9998474,0.00004175745,0.00002318868,0.00002503736,0.00003203796,0.00003041531],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002312768,0.00004732049,0.001267572,0.0001164335,0.0000227314,0.0005120123,0.0002021962,0.0009892794,0.9230456,0.04466315,0.001312359,0.02759],"study_design_scores_gemma":[0.00009480667,0.0004311939,0.05314007,0.0001451078,0.00008720799,0.004704431,0.001018394,0.01449282,0.7496151,0.0701718,0.1059596,0.0001395918],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7551941,0.05492386,0.128338,0.005963252,0.001211615,0.0001418031,0.001455156,0.000817929,0.05195428],"genre_scores_gemma":[0.9702884,0.01335814,0.006049402,0.0003990114,0.0002924101,0.0000696145,0.0004787728,0.00005087223,0.009013419],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0018825,"threshold_uncertainty_score":0.006297588,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004019403899192247,"score_gpt":0.2134537958714211,"score_spread":0.2094343919722288,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}