{"id":"W2162165620","doi":"10.1091/mbc.e09-07-0601","title":"Poleward Transport of TPX2 in the Mammalian Mitotic Spindle Requires Dynein, Eg5, and Microtubule Flux","year":2010,"lang":"en","type":"article","venue":"Molecular Biology of the Cell","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":86,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Institute of General Medical Sciences; New York State Department of Health - Wadsworth Center; National Institutes of Health; New York State Department of Health","keywords":"Kinetochore; Cell biology; Spindle apparatus; Biology; Dynein; Nocodazole; Microtubule; Spindle pole body; Mitosis; Spindle checkpoint; Astral microtubules; Microtubule nucleation; Microtubule organizing center; Cell division; Cytoskeleton; Genetics; Centrosome; Cell cycle; Cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009238377,0.0003295659,0.0001697039,0.0001487065,0.0002018117,0.0004942112,0.0001575653,0.0002374616,0.000684383],"category_scores_gemma":[0.0001021954,0.0002536493,0.0001571024,0.0001175684,0.0001476556,0.0003473086,0.0002732242,0.0002996084,0.0003141308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004683385,"about_ca_system_score_gemma":0.0002147384,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00140573,"about_ca_topic_score_gemma":0.002479991,"domain_scores_codex":[0.9999251,0.000006731549,0.000006551513,0.00002177628,0.00002636468,0.00001345194],"domain_scores_gemma":[0.9999346,0.000007850846,0.00001701762,0.00000925663,0.00001298609,0.00001824952],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004504558,0.000004981184,0.0002363474,0.00001310049,0.000001534809,0.00004527108,0.000009121834,0.00004086567,0.9990332,0.0001101156,0.00001353319,0.0004469017],"study_design_scores_gemma":[0.00001917015,0.00007296622,0.01608589,0.000005959354,0.00001030307,0.0002898812,0.00003595682,0.00200886,0.9796578,0.00005650089,0.001752611,0.000004176479],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965459,0.0004756399,0.001922657,0.00003536511,0.000008060131,0.000007937342,0.0001256206,0.00002910703,0.0008497298],"genre_scores_gemma":[0.9935644,0.0004486315,0.001553959,0.00002850377,0.000005238809,0.00001504092,0.0006618985,0.00002333087,0.003699098],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00140573,"threshold_uncertainty_score":0.003398061,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003814603844784987,"score_gpt":0.2201454297133095,"score_spread":0.2163308258685245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}