{"id":"W2162202488","doi":"10.1128/iai.69.1.159-169.2001","title":"Description of Staphylococcus Serine Protease ( <i>ssp</i> ) Operon in <i>Staphylococcus aureus</i> and Nonpolar Inactivation of <i>sspA</i> -Encoded Serine Protease","year":2001,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":166,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's College Hospital; University of Toronto; Mount Sinai Hospital; Sunnybrook Health Science Centre","funders":"National Institute of Allergy and Infectious Diseases; Medical Research Council","keywords":"Operon; Staphylococcus aureus; Protease; Biology; Serine protease; Cysteine protease; Microbiology; Cysteine; Virulence; Serine; Biochemistry; Escherichia coli; Gene; Molecular biology; Bacteria; Enzyme; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001103159,0.0004243873,0.0002914859,0.0002419074,0.0001445508,0.0003243023,0.0002333749,0.0003025935,0.0004559244],"category_scores_gemma":[0.0002193908,0.0001824976,0.0005720636,0.0001992821,0.0001926914,0.0000900546,0.0003185718,0.0004739126,0.0004863025],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003331329,"about_ca_system_score_gemma":0.0003588815,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001331558,"about_ca_topic_score_gemma":0.0009456871,"domain_scores_codex":[0.9997556,0.00004136872,0.00003702769,0.0000407778,0.00008800331,0.00003729509],"domain_scores_gemma":[0.9997643,0.00003184771,0.00009999204,0.00002814859,0.00002638292,0.00004937009],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003636948,0.0000197121,0.0002556014,0.00001850504,0.000002330248,0.0001016376,0.00001593168,0.00006515576,0.9987784,0.00005868972,0.00001293957,0.0006347764],"study_design_scores_gemma":[0.00002383126,0.0003112583,0.01277341,0.00001561007,0.0000279341,0.001453242,0.00008266431,0.001911595,0.9812701,0.0000974648,0.002016136,0.00001674474],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9873515,0.0003604015,0.01017791,0.0001054793,0.00003152723,0.0001025524,0.0007675448,0.0001371042,0.0009660117],"genre_scores_gemma":[0.9849014,0.0002463795,0.01088685,0.00005670226,0.00001377184,0.00009194141,0.002523456,0.00006056607,0.001219111],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001331558,"threshold_uncertainty_score":0.002647638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01923484891249074,"score_gpt":0.2617703497158637,"score_spread":0.2425355008033729,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}