{"id":"W2162221992","doi":"10.1016/j.carres.2013.03.018","title":"Clostridium difficile PSI polysaccharide: synthesis of pentasaccharide repeating block, conjugation to exotoxin B subunit, and detection of natural anti-PSI IgG antibodies in horse serum","year":2013,"lang":"en","type":"article","venue":"Carbohydrate Research","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Exotoxin; Chemistry; Polysaccharide; Microbiology; Clostridium difficile; Antibody; Linker; Protein subunit; Clostridium difficile toxin A; Stereochemistry; Biochemistry; Toxin; Antibiotics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001802836,0.000337604,0.0008853879,0.00188253,0.0002040148,0.00008772722,0.0003077216,0.0002462447,0.0001158019],"category_scores_gemma":[0.002947017,0.0003142494,0.0001504516,0.002374174,0.0004283645,0.0002491457,0.0004203023,0.001034782,0.00003849818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000322234,"about_ca_system_score_gemma":0.0003499153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005850276,"about_ca_topic_score_gemma":0.0003294407,"domain_scores_codex":[0.9953421,0.0004807683,0.001022311,0.000739178,0.001393473,0.001022184],"domain_scores_gemma":[0.9964285,0.0008845993,0.0002044809,0.0007216883,0.001364855,0.0003958205],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003103585,0.0002621092,0.01584651,0.0005491551,0.00007304394,0.00004637238,0.0004911177,0.00002134879,0.9750879,0.00002723804,0.00009514079,0.007189691],"study_design_scores_gemma":[0.0009167329,0.0004997106,0.03765602,0.0006327369,0.00004469111,0.00003270198,0.002325533,0.003400504,0.9541981,0.00003096094,0.00001832525,0.000243951],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956619,0.0008338662,0.000003324978,0.001033464,0.0001346486,0.001928084,0.00005940221,0.00004418705,0.000301114],"genre_scores_gemma":[0.9984934,0.0007620623,0.00008433636,0.00002106231,0.0001386424,0.0001949345,0.00001443461,0.00006092861,0.0002301879],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02180951,"threshold_uncertainty_score":0.999931,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03290666807755493,"score_gpt":0.3234819334086616,"score_spread":0.2905752653311067,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}