{"id":"W2162221992","doi":"10.1016/j.carres.2013.03.018","title":"Clostridium difficile PSI polysaccharide: synthesis of pentasaccharide repeating block, conjugation to exotoxin B subunit, and detection of natural anti-PSI IgG antibodies in horse serum","year":2013,"lang":"en","type":"article","venue":"Carbohydrate Research","topic":"Clostridium difficile and Clostridium perfringens research","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Exotoxin; Chemistry; Polysaccharide; Microbiology; Clostridium difficile; Antibody; Linker; Protein subunit; Clostridium difficile toxin A; Stereochemistry; Biochemistry; Toxin; Antibiotics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002208901,0.0004142952,0.0001059118,0.0001588913,0.0001559801,0.0001314592,0.0002095008,0.0002483432,0.0006228915],"category_scores_gemma":[0.0002036299,0.0001514622,0.0001996368,0.0001854958,0.000166755,0.0001509391,0.0001387612,0.0003700848,0.0002821637],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002927355,"about_ca_system_score_gemma":0.0003815615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001248602,"about_ca_topic_score_gemma":0.001292471,"domain_scores_codex":[0.999902,0.00002114753,0.000008621249,0.00001627107,0.00002195203,0.00003009052],"domain_scores_gemma":[0.9998909,0.00001975733,0.00002327841,0.00002018262,0.00001785171,0.00002797015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007743618,0.00002944642,0.000145592,0.00001924572,0.000002097375,0.00003776001,0.000009337073,0.00006842444,0.9986309,0.00008060916,0.00001465481,0.0008843514],"study_design_scores_gemma":[0.00001349085,0.0004566691,0.001893884,0.000002554858,0.000008244761,0.000114087,0.000007950445,0.000457,0.9964399,0.00002667001,0.0005772665,0.000002226066],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9861943,0.0003529054,0.01168213,0.00007372718,0.00001844185,0.0000667664,0.0001461365,0.00005020431,0.001415311],"genre_scores_gemma":[0.9869256,0.0004865374,0.009558598,0.00004270431,0.000008203803,0.00003377568,0.0007049142,0.00001540395,0.002224254],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001248602,"threshold_uncertainty_score":0.002482653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03290666807755493,"score_gpt":0.3234819334086616,"score_spread":0.2905752653311067,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}