{"id":"W2162262394","doi":"10.1086/598222","title":"Rosiglitazone Modulates the Innate Immune Response to<i>Plasmodium falciparum</i>Infection and Improves Outcome in Experimental Cerebral Malaria","year":2009,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Toronto General Hospital; University Health Network","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Ontario Genomics; Ontario Genomics Institute; Genome Canada","keywords":"Plasmodium berghei; Plasmodium chabaudi; Cerebral Malaria; Parasitemia; Immunology; Malaria; Plasmodium falciparum; Rosiglitazone; Immune system; Biology; Medicine; Pharmacology; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001297986,0.0003607023,0.0004453969,0.000209957,0.0001548695,0.0002457115,0.0002346903,0.0002842081,0.0006801112],"category_scores_gemma":[0.0001302155,0.00009500734,0.0001592341,0.000163711,0.0002585689,0.0001728532,0.0001025117,0.0008492813,0.0001771447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001392782,"about_ca_system_score_gemma":0.0001928693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002710455,"about_ca_topic_score_gemma":0.0006301576,"domain_scores_codex":[0.9999421,0.00001540261,0.000005891861,0.000007216719,0.000009466351,0.00002007137],"domain_scores_gemma":[0.9999171,0.000009196012,0.00003690379,0.000009923337,0.000006006033,0.00002083595],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006857041,0.001223788,0.0006335364,0.0002885289,0.00005145314,0.0002233816,0.00003943499,0.000286574,0.9680017,0.0003561019,0.0003979122,0.02164058],"study_design_scores_gemma":[0.001231878,0.01466986,0.01193423,0.00005054351,0.0001771489,0.0004973454,0.00008881996,0.001215689,0.9636638,0.0004148828,0.006032325,0.00002357172],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957442,0.00222253,0.0008501968,0.0002346655,0.00005981764,0.000032874,0.0001141254,0.0001132807,0.000628275],"genre_scores_gemma":[0.9921171,0.004076856,0.001339588,0.0001295288,0.00005970642,0.00007447895,0.0003006549,0.00001803362,0.001884006],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006801112,"threshold_uncertainty_score":0.002275229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007023773298615413,"score_gpt":0.2572411026780615,"score_spread":0.2502173293794461,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}