{"id":"W2162288626","doi":"10.1002/anie.201403939","title":"Total Syntheses of Hyperforin and Papuaforins A–C, and Formal Synthesis of Nemorosone through a Gold(I)‐Catalyzed Carbocyclization","year":2014,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Synthesis of Organic Compounds","field":"Medicine","cited_by":77,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Hyperforin; Total synthesis; Chemistry; Catalysis; Nonane; Combinatorial chemistry; Enol; Formal synthesis; Stereochemistry; Organic chemistry; Nanotechnology; Materials science; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001936027,0.0001360333,0.0003121888,0.00009775408,0.00003016111,0.00001326039,0.00007282121,0.00008888701,0.0001025006],"category_scores_gemma":[0.001088323,0.0001274124,0.0000623757,0.00007156651,0.0001483749,0.0003671326,0.0000782022,0.00006987021,0.000001530991],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000498309,"about_ca_system_score_gemma":0.00002750601,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001096831,"about_ca_topic_score_gemma":0.00000734687,"domain_scores_codex":[0.9989706,0.00001498888,0.0003394745,0.0002082957,0.0003377882,0.0001288392],"domain_scores_gemma":[0.9989849,0.0004201197,0.0002091635,0.0001609603,0.0001677497,0.00005711861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004867312,0.0002914997,0.01584247,0.0004296635,0.00028451,0.000003566038,0.0005485178,0.000003647644,0.9588144,0.001876827,0.0004337293,0.02098441],"study_design_scores_gemma":[0.0006398378,0.00008279828,0.03157951,0.0003380485,0.0001342753,0.0001438743,0.0001632609,0.0003426451,0.9657043,0.0002963053,0.0004684196,0.0001067357],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9891368,0.0001287943,0.001385459,0.0007730554,0.0002770808,0.0001423366,0.00005918245,0.00003052435,0.008066796],"genre_scores_gemma":[0.9979783,0.0002002956,0.001121621,0.00003403879,0.0004950929,0.00002062701,0.00006548042,0.00001922319,0.00006529716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02087767,"threshold_uncertainty_score":0.5195725,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01451660467851033,"score_gpt":0.2488745249189161,"score_spread":0.2343579202404057,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}