{"id":"W2162300073","doi":"10.1038/sj.onc.1205546","title":"Lack of functional pRb results in attenuated recovery of mRNA synthesis and increased apoptosis following UV radiation in human breast cancer cells","year":2002,"lang":"en","type":"article","venue":"Oncogene","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Regional Cancer Foundation; University of Ottawa","funders":"","keywords":"Apoptosis; Biology; Cancer cell; Molecular biology; DNA damage; Cell culture; Null cell; Retinoblastoma protein; UVB-induced apoptosis; Cancer research; Programmed cell death; Cell cycle; Caspase; Cancer; DNA; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003134583,0.0003606485,0.0005784169,0.0004558377,0.0002944887,0.000442828,0.0003484066,0.0004286526,0.002167639],"category_scores_gemma":[0.0003131459,0.0004013438,0.0004427595,0.0003794287,0.0004367364,0.0002785271,0.0002050143,0.001098748,0.0007572619],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003771636,"about_ca_system_score_gemma":0.0003270314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001472744,"about_ca_topic_score_gemma":0.001086166,"domain_scores_codex":[0.999633,0.0000789267,0.00004662981,0.00005915284,0.00008319603,0.00009912994],"domain_scores_gemma":[0.9996738,0.00009626446,0.0000482258,0.00008398434,0.00003109374,0.00006659764],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003116298,0.00005304578,0.0001267052,0.00002899708,0.000009216164,0.00005941129,0.00001778714,0.0000497074,0.9986253,0.0000873526,0.00004728972,0.0005835891],"study_design_scores_gemma":[0.00002660158,0.0003195352,0.00302765,0.00000428244,0.00001834047,0.000337969,0.00003725888,0.0003981038,0.9947838,0.00003140613,0.001011526,0.000003488592],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938815,0.002269504,0.002019403,0.0001758433,0.00006271948,0.00002918889,0.0006090555,0.0001234143,0.0008295157],"genre_scores_gemma":[0.993501,0.0008102282,0.001472401,0.00005342393,0.00001452106,0.00005177478,0.0014209,0.00004069251,0.002634899],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002167639,"threshold_uncertainty_score":0.007251501,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02966096900858963,"score_gpt":0.2628215354592175,"score_spread":0.2331605664506279,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}