{"id":"W2162362966","doi":"10.1111/mmi.12095","title":"<scp>FadD</scp>3 is an acyl‐<scp>CoA</scp> synthetase that initiates catabolism of cholesterol rings <scp>C</scp> and <scp>D</scp> in actinobacteria","year":2012,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Steroid Chemistry and Biochemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Catabolism; Biochemistry; Biology; FADD; Enzyme; Steroid; Mutant; Metabolite; Actinobacteria; Gene; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0006606698,0.001226416,0.001157489,0.000233011,0.0002166772,0.0001304707,0.001213229,0.001849122,0.00001661742],"category_scores_gemma":[0.001486996,0.001263996,0.0004028504,0.0003423874,0.0008033146,0.00008704755,0.001075118,0.0008295938,0.00004610169],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007095393,"about_ca_system_score_gemma":0.0001701518,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001026589,"about_ca_topic_score_gemma":0.000019527,"domain_scores_codex":[0.9944884,0.0004069426,0.001045489,0.001778008,0.0002398982,0.002041288],"domain_scores_gemma":[0.9962033,0.0004497835,0.0008130069,0.001623403,0.0002378334,0.0006726503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001224607,0.0005264915,0.02550653,0.0003591587,0.0003133208,0.0000528457,0.001336932,0.000004304393,0.9658763,0.000009009698,0.005785065,0.000217728],"study_design_scores_gemma":[0.00158884,0.0002716372,0.007833257,0.0001126704,0.0001823014,0.0007303002,0.001604478,0.000004820172,0.9028201,0.00003185822,0.08466492,0.0001548317],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9881429,0.008073411,0.0001010427,0.00004281959,0.0004506037,0.0005383949,0.001022357,0.00008033598,0.001548108],"genre_scores_gemma":[0.9922744,0.0008480522,0.0004196197,0.001431013,0.0005020383,0.0001101562,0.002508702,0.0001774322,0.001728606],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07887986,"threshold_uncertainty_score":0.9994467,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01229867982568802,"score_gpt":0.2356421064702777,"score_spread":0.2233434266445897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}