{"id":"W2162362966","doi":"10.1111/mmi.12095","title":"<scp>FadD</scp>3 is an acyl‐<scp>CoA</scp> synthetase that initiates catabolism of cholesterol rings <scp>C</scp> and <scp>D</scp> in actinobacteria","year":2012,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Steroid Chemistry and Biochemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Catabolism; Biochemistry; Biology; FADD; Enzyme; Steroid; Mutant; Metabolite; Actinobacteria; Gene; Apoptosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009104334,0.0006047122,0.0003513017,0.0002663349,0.0003490118,0.0003950606,0.0002729053,0.0003645704,0.000689597],"category_scores_gemma":[0.0001657171,0.0001708376,0.0004890996,0.0003005819,0.0005018703,0.0001611139,0.0002385317,0.0004392528,0.0006814896],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001114168,"about_ca_system_score_gemma":0.0004013373,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005314763,"about_ca_topic_score_gemma":0.003464967,"domain_scores_codex":[0.9998823,0.00001197633,0.000008541054,0.00003484795,0.00004023303,0.00002192797],"domain_scores_gemma":[0.999896,0.00001480672,0.00002384229,0.00001372617,0.00001890683,0.00003257006],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001871375,0.00001853923,0.001564578,0.0000823378,0.00001110799,0.0001690495,0.00001446218,0.0002352725,0.9936052,0.0001450067,0.0001196299,0.003847707],"study_design_scores_gemma":[0.00001396346,0.00007595022,0.007329069,0.000004565987,0.000008795591,0.0008392228,0.00002247801,0.001279686,0.9869738,0.00009181103,0.003347883,0.00001276705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9807261,0.002724532,0.0116533,0.0001916966,0.00006296213,0.00007128376,0.002003887,0.0005088149,0.002057425],"genre_scores_gemma":[0.9900586,0.0006547888,0.005255043,0.000053016,0.000007526412,0.00001620084,0.002221582,0.00004413018,0.001689141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005314763,"threshold_uncertainty_score":0.01056767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01229867982568802,"score_gpt":0.2356421064702777,"score_spread":0.2233434266445897,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}