{"id":"W2162376892","doi":"10.1128/aac.46.11.3348-3355.2002","title":"Mycothiol-Deficient <i>Mycobacterium smegmatis</i> Mutants Are Hypersensitive to Alkylating Agents, Free Radicals, and Antibiotics","year":2002,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Mycobacterium research and diagnosis","field":"Medicine","cited_by":194,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; British Columbia Lung Association; Fogarty International Center; National Science Foundation","keywords":"Mutant; Mycobacterium smegmatis; Rifamycin; Mutagenesis; Transposable element; Biology; Microbiology; Biochemistry; Transposon mutagenesis; Chemistry; Molecular biology; Mycobacterium tuberculosis; Gene; Antibiotics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001621635,0.0003408436,0.0005464856,0.0001500784,0.0002415053,0.0001565936,0.0001272312,0.0001669717,0.000607521],"category_scores_gemma":[0.0001301558,0.0002949311,0.0000990302,0.000240619,0.0001514507,0.0001134455,0.0001505768,0.0002368337,0.00006941224],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004005732,"about_ca_system_score_gemma":0.00001890709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008514305,"about_ca_topic_score_gemma":0.00001253356,"domain_scores_codex":[0.9980238,0.00005047017,0.0003655636,0.000594492,0.0003305159,0.0006351694],"domain_scores_gemma":[0.9987162,0.00007547846,0.0001212683,0.0003998022,0.0001133216,0.0005739549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.0005174396,0.001254439,0.3554905,0.0005550857,0.0004031784,0.0005827447,0.003003955,0.000002566347,0.2473994,0.00003801685,0.3603279,0.03042489],"study_design_scores_gemma":[0.008154458,0.0008134971,0.8316035,0.001219338,0.0001655095,0.000588314,0.0005184727,0.001119087,0.05644572,0.00001644922,0.09845638,0.0008992763],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985957,0.00014958,0.00005290865,0.01173106,0.0001656704,0.0006542462,0.0002171884,0.0000705186,0.001001854],"genre_scores_gemma":[0.9643799,0.006240347,0.001328171,0.02725504,0.0002487384,0.000002305484,0.00003258658,0.00005912158,0.0004538114],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.476113,"threshold_uncertainty_score":0.9999503,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0249683604827962,"score_gpt":0.2616717127947605,"score_spread":0.2367033523119643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}