{"id":"W2162376892","doi":"10.1128/aac.46.11.3348-3355.2002","title":"Mycothiol-Deficient <i>Mycobacterium smegmatis</i> Mutants Are Hypersensitive to Alkylating Agents, Free Radicals, and Antibiotics","year":2002,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Mycobacterium research and diagnosis","field":"Medicine","cited_by":194,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; British Columbia Lung Association; Fogarty International Center; National Science Foundation","keywords":"Mutant; Mycobacterium smegmatis; Rifamycin; Mutagenesis; Transposable element; Biology; Microbiology; Biochemistry; Transposon mutagenesis; Chemistry; Molecular biology; Mycobacterium tuberculosis; Gene; Antibiotics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009968752,0.0004593589,0.0003339135,0.0001954511,0.00012379,0.0002972882,0.0002334757,0.0003032454,0.000672143],"category_scores_gemma":[0.000232725,0.000204875,0.0002755793,0.0002028177,0.0002199215,0.0001384426,0.0002333338,0.000340783,0.0004707207],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002747154,"about_ca_system_score_gemma":0.0001499748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001463487,"about_ca_topic_score_gemma":0.001381103,"domain_scores_codex":[0.9997862,0.00002688751,0.00003070995,0.00003753984,0.00007158244,0.00004698755],"domain_scores_gemma":[0.9997279,0.00003887977,0.00011803,0.00003198724,0.00003393885,0.00004927785],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003249248,0.000008956232,0.0002563086,0.00001469244,0.000003173257,0.00004192586,0.000008470852,0.00002432966,0.9992397,0.00001726975,0.00002021433,0.000332422],"study_design_scores_gemma":[0.000007119512,0.0001694361,0.00669951,0.00000515674,0.00001492562,0.000696293,0.0000377631,0.0004149643,0.9907838,0.00002416382,0.001140812,0.000006104387],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969494,0.0004155381,0.001443345,0.00004610912,0.00001728357,0.00001526569,0.0003979256,0.0001221468,0.0005930373],"genre_scores_gemma":[0.9948878,0.0002793818,0.002184946,0.00005002742,0.000007622245,0.00002530354,0.0009649386,0.0000557224,0.001544312],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001463487,"threshold_uncertainty_score":0.002909899,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0249683604827962,"score_gpt":0.2616717127947605,"score_spread":0.2367033523119643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}