{"id":"W2162385422","doi":"10.1074/jbc.m508541200","title":"Structural Analysis of Mg2+ and Ca2+ Binding to CaBP1, a Neuron-specific Regulator of Calcium Channels","year":2005,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Ion channel regulation and function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":84,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"National Institute of Neurological Disorders and Stroke; National Eye Institute","keywords":"Regulator; Calcium; Chemistry; Neuron; Biophysics; Cell biology; Neuroscience; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001951592,0.0001195062,0.0003319814,0.00009203791,0.00003018247,0.000008685841,0.0001245851,0.0001887499,0.00009210943],"category_scores_gemma":[0.00009969848,0.00008774786,0.0002075839,0.0002544897,0.00008877576,0.000005427338,0.00006238062,0.00009174512,3.705041e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001833105,"about_ca_system_score_gemma":0.00002153513,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001431127,"about_ca_topic_score_gemma":5.057466e-7,"domain_scores_codex":[0.9990369,0.00002941301,0.0004774976,0.0001790429,0.000143222,0.0001339205],"domain_scores_gemma":[0.9991388,0.0000199414,0.0003702968,0.0001377285,0.0002075891,0.0001256215],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002324824,0.00002591221,0.003055121,0.0000129955,0.0001616794,0.000001280945,0.00003578189,0.002043513,0.9928618,0.000006779952,0.0003236823,0.001238984],"study_design_scores_gemma":[0.0004038376,0.0002779398,0.01922139,0.00001452285,0.00007938639,0.00004484794,0.0001034361,0.0004735512,0.9746779,0.000008729908,0.00457583,0.0001186126],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986519,0.0004216798,0.0004714952,0.0001882328,0.0001252819,0.0000424256,0.00002427444,0.000002437456,0.00007225778],"genre_scores_gemma":[0.9987276,0.00009435147,0.0004079187,0.00005009743,0.0005289024,8.883989e-7,0.00003117302,0.0000055764,0.0001535226],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01818387,"threshold_uncertainty_score":0.3578254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03217956379986424,"score_gpt":0.2700088621617616,"score_spread":0.2378292983618973,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}