{"id":"W2162514497","doi":"10.2337/db11-0085","title":"Glycation of LDL by Methylglyoxal Increases Arterial Atherogenicity","year":2011,"lang":"en","type":"article","venue":"Diabetes","topic":"Advanced Glycation End Products research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":166,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Heart Institute","funders":"British Heart Foundation; Heart and Stroke Foundation of Canada; American Diabetes Association","keywords":"Methylglyoxal; Chemistry; Apolipoprotein B; Glycation; Scavenger receptor; Proteoglycan; In vivo; LDL receptor; Low-density lipoprotein; Receptor; Biochemistry; In vitro; Arginine; Lipoprotein; Internal medicine; Endocrinology; Cholesterol; Amino acid; Biology; Extracellular matrix; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00016547,0.0000746299,0.00008879122,0.0000234484,0.00003322577,0.000003879176,0.0001400751,0.00006054819,0.0001133275],"category_scores_gemma":[0.0002836748,0.00007133982,0.00003821642,0.00006776088,0.00008804259,0.000005232048,0.00005422239,0.00004201732,0.00001135298],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004895063,"about_ca_system_score_gemma":0.00002938791,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003127435,"about_ca_topic_score_gemma":0.000002068445,"domain_scores_codex":[0.9993439,0.00008555479,0.000131158,0.0001965503,0.00009376542,0.0001491287],"domain_scores_gemma":[0.9994972,0.00001550562,0.0000660911,0.0002670943,0.0001085542,0.0000456038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004732304,0.00009122246,0.005857255,0.00001118655,0.00003042977,5.673084e-8,0.00004370839,9.113048e-7,0.9904798,0.00007871006,0.0007515943,0.002607813],"study_design_scores_gemma":[0.0002056252,0.0001322818,0.00286445,0.000002702854,0.000006805046,2.40155e-7,0.00002263024,0.000005567721,0.9903509,0.0003653747,0.005966201,0.00007721705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980227,0.0006175063,0.0005090566,0.00001984627,0.00004822203,0.000100945,0.00005108516,0.000008405295,0.000622237],"genre_scores_gemma":[0.9981999,0.00006017897,0.001186052,0.0000467202,0.00009513432,0.00001977166,0.0001908375,0.00001213824,0.0001892027],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005214606,"threshold_uncertainty_score":0.2909153,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01931136729455148,"score_gpt":0.2697603750008453,"score_spread":0.2504490077062939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}