{"id":"W2162518856","doi":"10.1534/genetics.104.040105","title":"In Vivo Characterization of the Nonessential Budding Yeast Anaphase-Promoting Complex/Cyclosome Components Swm1p, Mnd2p and Apc9p","year":2005,"lang":"en","type":"article","venue":"Genetics","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Cancer Institute","keywords":"Biology; Mutant; Anaphase; Cell biology; Mitosis; Anaphase-promoting complex; Proteolysis; Cell division control protein 4; Synthetic lethality; Protein subunit; Yeast; Cell cycle; Saccharomyces cerevisiae; Ubiquitin; Mutation; Molecular biology; Genetics; Cell; Biochemistry; Ubiquitin ligase; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001608825,0.0003299331,0.00017426,0.0002326919,0.0001759215,0.0003922057,0.0002494498,0.0001983341,0.0006764827],"category_scores_gemma":[0.0002831255,0.0002330461,0.0001353493,0.0001835921,0.0001733568,0.0002021233,0.000258875,0.0004109169,0.0003994451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004251911,"about_ca_system_score_gemma":0.0002402005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007385859,"about_ca_topic_score_gemma":0.001422597,"domain_scores_codex":[0.9999048,0.00001225204,0.0000129616,0.00002223599,0.00003750025,0.00001023664],"domain_scores_gemma":[0.9998056,0.00004395841,0.00004821142,0.00003403409,0.00002881104,0.00003928347],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004959217,0.00001158297,0.0003768754,0.00002847896,0.000002857144,0.00004632658,0.000008474291,0.000062994,0.9986172,0.0000725825,0.00001490499,0.0007081694],"study_design_scores_gemma":[0.000006130502,0.00003727766,0.004346197,0.000002763734,0.0000107083,0.0002962528,0.00001361208,0.0007164276,0.9924343,0.00003916076,0.002094797,0.000002357632],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940024,0.001521895,0.002911429,0.00008516109,0.00001114542,0.00001415124,0.0006406796,0.000036142,0.0007769865],"genre_scores_gemma":[0.9900249,0.0008438073,0.004040975,0.00004580786,0.000007614066,0.00002658589,0.003100631,0.00004715576,0.001862305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007385859,"threshold_uncertainty_score":0.003084958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01005885059668281,"score_gpt":0.2320878668901487,"score_spread":0.2220290162934658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}