{"id":"W2162518856","doi":"10.1534/genetics.104.040105","title":"In Vivo Characterization of the Nonessential Budding Yeast Anaphase-Promoting Complex/Cyclosome Components Swm1p, Mnd2p and Apc9p","year":2005,"lang":"en","type":"article","venue":"Genetics","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"National Cancer Institute","keywords":"Biology; Mutant; Anaphase; Cell biology; Mitosis; Anaphase-promoting complex; Proteolysis; Cell division control protein 4; Synthetic lethality; Protein subunit; Yeast; Cell cycle; Saccharomyces cerevisiae; Ubiquitin; Mutation; Molecular biology; Genetics; Cell; Biochemistry; Ubiquitin ligase; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007245705,0.0001063974,0.0001158721,0.00003551749,0.00005224172,0.00001421977,0.0001400924,0.0000879484,0.00001416139],"category_scores_gemma":[0.000007424235,0.00009776934,0.00003916473,0.00007944532,0.00006345108,0.000003995888,0.0001458476,0.00005445667,0.000001191026],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008781742,"about_ca_system_score_gemma":0.00001667422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008279934,"about_ca_topic_score_gemma":0.00006901786,"domain_scores_codex":[0.9992999,0.00004022483,0.0002220778,0.0001914119,0.00008625072,0.0001601786],"domain_scores_gemma":[0.9996136,0.000002938898,0.0001085756,0.000205417,0.00003582581,0.0000335995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001077599,0.00005953948,0.008030149,0.00002265785,0.00001264099,3.883058e-7,0.0001101022,0.00007670461,0.9906479,0.0000127029,0.00003883397,0.000977597],"study_design_scores_gemma":[0.0005311887,0.00004275705,0.02896558,0.00002698074,0.00001388445,0.0000136583,0.00002194401,0.003518573,0.9543628,0.000006718811,0.01236639,0.0001295858],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988451,0.0001093104,0.0005228923,0.0001112966,0.0001067468,0.0001836912,0.00006063524,0.000003230782,0.00005709442],"genre_scores_gemma":[0.9986042,0.000217634,0.0006424795,0.0001559571,0.0002045406,0.000005567074,0.00008072095,0.00001624415,0.00007268977],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03628517,"threshold_uncertainty_score":0.3986918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01005885059668281,"score_gpt":0.2320878668901487,"score_spread":0.2220290162934658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}