{"id":"W2162566840","doi":"10.1038/onc.2011.88","title":"New model systems provide insights into Myc-induced transformation","year":2011,"lang":"en","type":"article","venue":"Oncogene","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Ontario Ministry of Health and Long-Term Care; University of Pennsylvania; Cancer Research Institute","keywords":"Biology; Carcinogenesis; Context (archaeology); Cell biology; Transformation (genetics); Gene isoform; Mutant; Function (biology); Computational biology; Cell culture; Cell growth; Cancer research; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002642696,0.0007548368,0.0007010722,0.0004968359,0.000637071,0.001152206,0.0006535626,0.0009309177,0.002819965],"category_scores_gemma":[0.0003638311,0.0002643555,0.0005760869,0.0002684593,0.0009758784,0.001730421,0.0006722202,0.00187232,0.0006459773],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001253157,"about_ca_system_score_gemma":0.0002760265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004182126,"about_ca_topic_score_gemma":0.0005727455,"domain_scores_codex":[0.9998484,0.00004077295,0.000008399687,0.00003728621,0.00004383567,0.00002135102],"domain_scores_gemma":[0.9998492,0.00005777969,0.00002028989,0.00004576437,0.000008603145,0.00001833277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003169448,0.0001215,0.0002486848,0.000221685,0.00002608605,0.0002794451,0.0001062986,0.007038473,0.5267493,0.4543964,0.001968849,0.008526256],"study_design_scores_gemma":[0.0002276843,0.0005349619,0.0006876047,0.00003174341,0.0001229696,0.001390209,0.0001291397,0.07866053,0.6211604,0.2264004,0.07057248,0.00008189212],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6042779,0.008828521,0.3233265,0.006540535,0.00124881,0.0002199415,0.001784563,0.001944751,0.0518285],"genre_scores_gemma":[0.9552495,0.003858809,0.02938796,0.0003302641,0.0001197353,0.0002534073,0.0006936827,0.000142606,0.009964004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002819965,"threshold_uncertainty_score":0.009433687,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02968029157545171,"score_gpt":0.2460365286542893,"score_spread":0.2163562370788376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}