{"id":"W2162566840","doi":"10.1038/onc.2011.88","title":"New model systems provide insights into Myc-induced transformation","year":2011,"lang":"en","type":"article","venue":"Oncogene","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ontario Institute for Cancer Research; University of Toronto","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Ontario Ministry of Health and Long-Term Care; University of Pennsylvania; Cancer Research Institute","keywords":"Biology; Carcinogenesis; Context (archaeology); Cell biology; Transformation (genetics); Gene isoform; Mutant; Function (biology); Computational biology; Cell culture; Cell growth; Cancer research; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008246154,0.0001216287,0.0001032821,0.00004482961,0.0000697541,0.00001617604,0.0001070518,0.0001236717,0.0000120411],"category_scores_gemma":[0.00001014625,0.0001118439,0.00006102013,0.00006561525,0.0000111248,0.00001011947,0.000022435,0.00004514143,0.00002193378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001998001,"about_ca_system_score_gemma":0.0001581838,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001403499,"about_ca_topic_score_gemma":0.00004395671,"domain_scores_codex":[0.999305,0.00003162769,0.0002057104,0.0002029483,0.000116915,0.0001377843],"domain_scores_gemma":[0.9995357,0.000001300335,0.00006726073,0.0002186949,0.00006026119,0.0001168049],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005402166,0.00002280427,0.000009967881,0.0000256677,0.00002066424,0.000001557112,0.0005478417,0.0006779646,0.9837671,0.001007326,0.000164468,0.01370064],"study_design_scores_gemma":[0.0004654347,0.0001219875,0.00003386696,0.00002158894,0.00001576894,0.00000680628,0.0000351161,0.01061601,0.9786446,0.0004972736,0.009365853,0.0001756805],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7629371,0.001202399,0.2291276,0.00003991914,0.000127592,0.000396335,0.000002283165,0.00003446324,0.006132233],"genre_scores_gemma":[0.9944918,0.00004528515,0.004544131,0.00007524074,0.0001732867,0.00002952768,0.00006881282,0.00001811255,0.0005537798],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2315547,"threshold_uncertainty_score":0.456086,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02968029157545171,"score_gpt":0.2460365286542893,"score_spread":0.2163562370788376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}