{"id":"W2162605540","doi":"10.1111/imm.12416","title":"Cyclin‐dependent kinase 5 regulates degranulation in human eosinophils","year":2014,"lang":"en","type":"article","venue":"Immunology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Cell biology; Cyclin-dependent kinase 5; Degranulation; Biology; Eosinophil peroxidase; Exocytosis; Small interfering RNA; Eosinophil; Kinase; Secretion; Molecular biology; Immunology; Protein kinase A; Mitogen-activated protein kinase kinase; Cell culture; Biochemistry; Transfection","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001737894,0.0001091296,0.0001255694,0.00007137262,0.00005535736,0.000008475403,0.0001161881,0.0002231087,0.00003781799],"category_scores_gemma":[0.00001909815,0.0001140411,0.00005396518,0.00005149308,0.00007142677,0.000003188036,0.0000265362,0.00009236585,0.00001463573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000124691,"about_ca_system_score_gemma":0.00001084248,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000977284,"about_ca_topic_score_gemma":0.0002757579,"domain_scores_codex":[0.9992064,0.00007629961,0.0002136231,0.0002540872,0.0000557963,0.0001937821],"domain_scores_gemma":[0.9996068,0.000005430853,0.00005392191,0.0002825518,0.0000285559,0.0000227078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005702095,0.00004571129,0.01188483,0.000004605255,0.0000133182,0.000003113724,0.00003547065,0.0000599584,0.9851534,0.0007703257,0.000008478559,0.001963791],"study_design_scores_gemma":[0.001425064,0.0003462909,0.2559561,0.00001468785,0.00001422868,0.00001500837,0.00002497322,0.0001290106,0.722182,0.002184144,0.01746229,0.0002462841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941368,0.0006334185,0.003936726,0.0001021677,0.0001905461,0.0001039488,0.000001944589,0.00001459252,0.0008798878],"genre_scores_gemma":[0.9976479,0.00006584693,0.00008446765,0.00006275553,0.0001169239,0.00001124079,0.001661112,0.00001403923,0.0003356669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2629714,"threshold_uncertainty_score":0.4650461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006863202400217991,"score_gpt":0.2258557554319373,"score_spread":0.2189925530317193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}