{"id":"W2162605540","doi":"10.1111/imm.12416","title":"Cyclin‐dependent kinase 5 regulates degranulation in human eosinophils","year":2014,"lang":"en","type":"article","venue":"Immunology","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Cell biology; Cyclin-dependent kinase 5; Degranulation; Biology; Eosinophil peroxidase; Exocytosis; Small interfering RNA; Eosinophil; Kinase; Secretion; Molecular biology; Immunology; Protein kinase A; Mitogen-activated protein kinase kinase; Cell culture; Biochemistry; Transfection","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009078171,0.0001858646,0.0001384825,0.0001754044,0.0001402038,0.0002877435,0.0000874773,0.0001296321,0.001745479],"category_scores_gemma":[0.0001015903,0.00008166537,0.0001560063,0.0001504827,0.00007735068,0.000105598,0.0001041772,0.0001976072,0.0005033742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003321163,"about_ca_system_score_gemma":0.0001865816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001005802,"about_ca_topic_score_gemma":0.001366398,"domain_scores_codex":[0.9999315,0.00001079716,0.000006088374,0.00001682695,0.00001411917,0.00002072565],"domain_scores_gemma":[0.9999617,0.000009427563,0.000009227741,0.000003900912,0.000006964854,0.000008851174],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004606919,0.0000411883,0.001393171,0.0001142813,0.00001113621,0.0002156669,0.00003521729,0.0001251215,0.9913484,0.0003526424,0.0003252689,0.005577212],"study_design_scores_gemma":[0.0001455903,0.0002797239,0.04865371,0.00002685159,0.00004766809,0.0009522252,0.00008431763,0.001640286,0.9266737,0.0001496348,0.02133806,0.000008187608],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9769851,0.01427895,0.002828329,0.0001848427,0.00006266624,0.00007358328,0.001463122,0.00007759635,0.004045845],"genre_scores_gemma":[0.9921126,0.003039685,0.001386453,0.00006827207,0.00001359987,0.00003937283,0.001246008,0.00001136933,0.002082544],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001745479,"threshold_uncertainty_score":0.005839229,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006863202400217991,"score_gpt":0.2258557554319373,"score_spread":0.2189925530317193,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}