{"id":"W2162617484","doi":"10.1016/j.vaccine.2010.04.018","title":"Mucosal HIV vaccines: A holy grail or a dud?","year":2010,"lang":"en","type":"review","venue":"Vaccine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Children's Hospital of Eastern Ontario; Variation Biotechnologies (Canada); University of Ottawa","funders":"Ontario HIV Treatment Network","keywords":"Immune system; Holy Grail; Immunology; Human immunodeficiency virus (HIV); Mucosal immunity; Innate immune system; Acquired immune system; AIDS Vaccines; Virology; Medicine; Immunity; Biology; Vaccine trial; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002416504,0.0006993117,0.002072652,0.000401568,0.0002101635,0.0000377334,0.000653272,0.00104724,0.01004681],"category_scores_gemma":[0.0002339773,0.0003975092,0.0005828002,0.0004377943,0.00002380342,0.00006740518,0.0002539975,0.001484449,0.03957333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008274308,"about_ca_system_score_gemma":0.0006396654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006017385,"about_ca_topic_score_gemma":0.0001742608,"domain_scores_codex":[0.9973733,0.0003127821,0.0006691993,0.0007075371,0.0000631353,0.0008739842],"domain_scores_gemma":[0.998209,0.0003955027,0.00025577,0.0009403146,0.00008752232,0.0001118932],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001458873,0.000314214,0.00004013256,0.002231094,0.0008462018,0.0002427742,0.00002558385,5.33205e-9,0.00006040768,0.00004958427,0.08613405,0.9099101],"study_design_scores_gemma":[0.002381849,0.000353282,0.00005734137,0.001442061,0.000743472,0.001029122,0.000007849599,4.189187e-8,0.00001792086,0.00000956959,0.9935607,0.0003968292],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007581116,0.9959711,0.000008314838,0.0001953765,0.0007798013,0.001163516,0.0007283136,0.0001677816,0.000909937],"genre_scores_gemma":[0.00002337362,0.9391923,0.00007305443,0.0000382104,0.0002312538,0.00042718,0.003655049,0.00008836221,0.05627123],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9095132,"threshold_uncertainty_score":0.9998477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03666900162953314,"score_gpt":0.3306769518031097,"score_spread":0.2940079501735766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}