{"id":"W2162640187","doi":"10.2174/1389450116666150416120559","title":"AMP-activated Protein Kinase As a Target For Pathogens: Friends Or Foes?","year":2016,"lang":"en","type":"review","venue":"Current Drug Targets","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier de l'Université Laval","funders":"","keywords":"AMPK; Protein kinase A; AMP-activated protein kinase; Pathogen; Reprogramming; Biology; Cell biology; Energy homeostasis; Kinase; Signal transduction; Cell metabolism; Intracellular; Cell; Microbiology; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003714302,0.0005647235,0.001116183,0.001224913,0.0003047792,0.0010471,0.0006875753,0.00125154,0.003887042],"category_scores_gemma":[0.0005188571,0.0002041915,0.0004099556,0.001236744,0.0005395982,0.00179883,0.000567749,0.002300454,0.002881746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004735866,"about_ca_system_score_gemma":0.0006267222,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000455112,"about_ca_topic_score_gemma":0.001034018,"domain_scores_codex":[0.9998661,0.00002769746,0.00001783327,0.00002494847,0.00004619369,0.00001711262],"domain_scores_gemma":[0.999786,0.00009282165,0.00002842154,0.000008761779,0.00005539875,0.00002868622],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001220982,0.00006139278,0.0001907941,0.01025745,0.00008453907,0.0004166319,0.00009008367,0.0001730606,0.002872103,0.006176932,0.05133311,0.9282217],"study_design_scores_gemma":[0.00001286236,0.00006604855,0.0003378209,0.001530889,0.00005707871,0.001606241,0.00005622123,0.00004881376,0.0004235934,0.002509227,0.9933396,0.00001151226],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000980744,0.9977956,0.00009068851,0.0007859328,0.0003329412,0.000001769862,0.0000103178,0.000006330496,0.0008782878],"genre_scores_gemma":[0.0008201621,0.9972245,0.00013738,0.0004533719,0.0003487471,0.000003438267,0.00002019275,0.00000226101,0.0009900032],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003887042,"threshold_uncertainty_score":0.01300341,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04560844869053157,"score_gpt":0.3567008922532459,"score_spread":0.3110924435627144,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}