{"id":"W2162675860","doi":"10.1016/j.immuni.2008.03.016","title":"Central Role of Defective Interleukin-2 Production in the Triggering of Islet Autoimmune Destruction","year":2008,"lang":"en","type":"article","venue":"Immunity","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":710,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"National Center for Research Resources; National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Juvenile Diabetes Research Foundation Australia; National Institutes of Health; Canadian Diabetes Association; Howard Hughes Medical Institute","keywords":"Biology; Islet; Immunology; Interleukin; Cytokine; Endocrinology; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01295378865531949,"score_gpt":0.2210484794718804,"score_spread":0.2080946908165609,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."},"direct_labels":[],"classifier":{"requested":true,"available":true,"version":"metacan-v1-d91a1de5be90","frame_rows_covered":4299418,"decision_targets":["metaresearch","metaepi_narrow","metaepi_broad","bibliometrics","sts","scholarly_communication","open_science","research_integrity","randomized_trial","nonrandomized_trial","observational","systematic_review","meta_analysis","case_report","qualitative","simulation_or_modeling","bench_or_experimental","theoretical_or_conceptual","not_applicable"],"score_encoding":"uint16_le_65535","score_resolution":0.000015259021896696422,"interpretation":"Scores imitate each teacher on the enriched screening sample; they are not calibrated prevalence probabilities for the full frame.","warning":null},"prediction":{"classifier_version":"metacan-v1-d91a1de5be90","candidate_union":["observational","bench_or_experimental"],"consensus_intersection":["observational","bench_or_experimental"],"score_encoding":"uint16_le_65535","score_resolution":0.000015259021896696422,"scores":{"codex":{"metaresearch":0.0012054627298390174,"metaepi_narrow":0.000015259021896696422,"metaepi_broad":0.00009155413138017853,"bibliometrics":0.000045777065690089265,"sts":0.0002746623941405356,"scholarly_communication":0.000045777065690089265,"open_science":0.000015259021896696422,"research_integrity":0.0006408789196612497,"randomized_trial":0.00009155413138017853,"nonrandomized_trial":0.00010681315327687495,"observational":0.07994201571679255,"systematic_review":0.000015259021896696422,"meta_analysis":0.00006103608758678569,"case_report":0.000030518043793392844,"qualitative":0.0050354772259098195,"simulation_or_modeling":0.0007476920729381247,"bench_or_experimental":0.4119325551232166,"theoretical_or_conceptual":0.0009613183794918746,"not_applicable":0.0039673456931410694,"design_other":0.007232776379034104},"gemma":{"metaresearch":0.00038147554741741054,"metaepi_narrow":0.000015259021896696422,"metaepi_broad":0.00007629510948348211,"bibliometrics":0.000030518043793392844,"sts":0.00024414435034714275,"scholarly_communication":0.000030518043793392844,"open_science":0.000045777065690089265,"research_integrity":0.0004882887006942855,"randomized_trial":0.00019836728465705348,"nonrandomized_trial":0.00019836728465705348,"observational":0.2556801709010452,"systematic_review":0.00009155413138017853,"meta_analysis":0.000015259021896696422,"case_report":0.00006103608758678569,"qualitative":0.004119935912108034,"simulation_or_modeling":0.00022888532845044633,"bench_or_experimental":0.5630426489662013,"theoretical_or_conceptual":0.00032043945983062486,"not_applicable":0.013214312962539101}},"interpretation":"Scores imitate each teacher on the enriched screening sample; they are not calibrated prevalence probabilities for the full frame."}}