{"id":"W2162690036","doi":"10.1039/c0ob00889c","title":"Atroposelective formation of dibenz[c,e]azepines via intramolecular direct arylation with centre-axis chirality transfer","year":2011,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Axial and Atropisomeric Chirality Synthesis","field":"Chemistry","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Engineering and Physical Sciences Research Council; University of Ottawa","keywords":"Chemistry; Intramolecular force; Axial chirality; Chirality (physics); Ring (chemistry); Acylation; Amine gas treating; Ring strain; Nitrogen atom; Stereochemistry; Computational chemistry; Catalysis; Organic chemistry; Enantioselective synthesis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008710031,0.0003758162,0.0001320218,0.0001069134,0.00008633434,0.0001480979,0.000239095,0.000143797,0.001807905],"category_scores_gemma":[0.0001032228,0.00009592909,0.00008532778,0.0001024002,0.0001486564,0.0001754502,0.0001728833,0.0003697297,0.0005380428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001615304,"about_ca_system_score_gemma":0.0001420074,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002789887,"about_ca_topic_score_gemma":0.0009022747,"domain_scores_codex":[0.9999337,0.000008958316,0.000004586881,0.00001858029,0.00001631117,0.00001782223],"domain_scores_gemma":[0.9999505,0.000007433987,0.00001955097,0.000005001959,0.000006413817,0.00001099556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007541504,0.00002701349,0.00008400561,0.00005777951,0.000004215486,0.0001213861,0.00001926638,0.0001454914,0.9948031,0.0005678844,0.0001339872,0.003960256],"study_design_scores_gemma":[0.00001221583,0.0001207362,0.000466385,0.000001435804,0.000003180912,0.000137138,0.000004062109,0.0002622412,0.9971542,0.00003421199,0.001801443,0.000002644823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9672533,0.00177,0.01107447,0.00009798988,0.00006157752,0.00009448575,0.0006700455,0.0001905126,0.0187876],"genre_scores_gemma":[0.9930655,0.0009016333,0.002693891,0.00002191486,0.00000983505,0.00001818291,0.0002461581,0.00001283666,0.003030104],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001807905,"threshold_uncertainty_score":0.006048024,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006937551877218747,"score_gpt":0.1752663154877147,"score_spread":0.168328763610496,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}