{"id":"W2162703316","doi":"10.1095/biolreprod.114.117754","title":"Effects of Four Chemotherapeutic Agents, Bleomycin, Etoposide, Cisplatin, and Cyclophosphamide, on DNA Damage and Telomeres in a Mouse Spermatogonial Cell Line1","year":2014,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":81,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Canadian Institutes of Health Research","keywords":"Etoposide; Telomere; Telomerase; Biology; Cisplatin; Bleomycin; DNA damage; Germ cell tumors; Cancer research; Telomerase reverse transcriptase; Molecular biology; Chemotherapy; DNA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001424347,0.0003966514,0.0002617497,0.0002856952,0.0001596118,0.0001746945,0.0001559097,0.0002958539,0.001034876],"category_scores_gemma":[0.0001045866,0.0001516718,0.000328186,0.0001644681,0.0001540591,0.0001214025,0.0001175808,0.000327085,0.0002159536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001667747,"about_ca_system_score_gemma":0.0001447118,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006326591,"about_ca_topic_score_gemma":0.001031876,"domain_scores_codex":[0.9998583,0.00003246751,0.00002192939,0.00002678387,0.00003554993,0.00002501844],"domain_scores_gemma":[0.9998535,0.00003137321,0.00003672709,0.00001880976,0.0000192333,0.00004040774],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002323536,0.00004414925,0.0003982554,0.00003923683,0.00001069799,0.00004374327,0.00001347382,0.00003418817,0.9982892,0.00001441742,0.0000281735,0.0008522413],"study_design_scores_gemma":[0.0000328535,0.002747073,0.01489117,0.000009421487,0.00004005146,0.0001970115,0.00002835384,0.0003365471,0.9799729,0.00002056165,0.001718837,0.000005261521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941878,0.003801283,0.0006787531,0.00005103671,0.00004206196,0.00004154081,0.0004010892,0.00004727774,0.000749098],"genre_scores_gemma":[0.991973,0.002783372,0.001448945,0.00008459794,0.00002142758,0.00006904077,0.001042717,0.00001497224,0.002561882],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001034876,"threshold_uncertainty_score":0.003462017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01044564324415572,"score_gpt":0.2464911107211682,"score_spread":0.2360454674770125,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}