{"id":"W2162735052","doi":"10.1128/jvi.76.24.12448-12456.2002","title":"Elevated Levels of Circulating Interleukin-18 in Human Immunodeficiency Virus-Infected Individuals: Role of Peripheral Blood Mononuclear Cells and Implications for AIDS Pathogenesis","year":2002,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":94,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôtel-Dieu de Montréal; Hotel Dieu Hospital; Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Institutes of Health Research","keywords":"Peripheral blood mononuclear cell; Immunology; Cytokine; Biology; Immune system; Proinflammatory cytokine; Lipopolysaccharide; Pathogenesis; Interleukin; Virology; In vitro; Inflammation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002631859,0.0001095745,0.0002892401,0.0001504667,0.00004887219,0.000006274576,0.0001683445,0.0001561491,0.00005344505],"category_scores_gemma":[0.0000718782,0.0001073097,0.0001227279,0.0001066539,0.0001027456,0.00001039284,0.00005648433,0.00009855301,2.261902e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007755981,"about_ca_system_score_gemma":0.00002487226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001225462,"about_ca_topic_score_gemma":0.000006372548,"domain_scores_codex":[0.9989145,0.00008587373,0.0006380105,0.0001317645,0.00005316395,0.0001766893],"domain_scores_gemma":[0.9991255,0.00002489816,0.0005080042,0.000158694,0.0001591965,0.00002369232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004187525,0.0002117521,0.01851436,0.00001653173,0.0001030164,5.766985e-7,0.0003707101,0.0001851753,0.9779865,0.00004523815,0.00001066904,0.002513576],"study_design_scores_gemma":[0.002027342,0.002261413,0.161965,0.00002109685,0.00009069353,0.00005383303,0.0003228033,0.0001470386,0.8323169,0.000345233,0.0003125054,0.0001360884],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973109,0.002145978,0.0002303989,0.00002534671,0.00002638226,0.0001157673,0.00004281673,0.000001636385,0.0001008235],"genre_scores_gemma":[0.9991246,0.0002380101,0.0005409178,0.00003418047,0.00002238509,0.000004884938,0.000007714383,0.00001570489,0.00001158304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1456696,"threshold_uncertainty_score":0.4375963,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01556904591514277,"score_gpt":0.2544064372959856,"score_spread":0.2388373913808428,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}