{"id":"W2162755299","doi":"10.1124/jpet.108.149815","title":"Up-Regulation of Transporters and Enzymes by the Vitamin D Receptor Ligands, 1α,25-Dihydroxyvitamin D3 and Vitamin D Analogs, in the Caco-2 Cell Monolayer","year":2009,"lang":"en","type":"article","venue":"Journal of Pharmacology and Experimental Therapeutics","topic":"Vitamin D Research Studies","field":"Medicine","cited_by":101,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"","keywords":"Calcitriol receptor; Vitamin D and neurology; Transporter; Vitamin; Chemistry; Monolayer; Enzyme; Biochemistry; Cell; Caco-2; Receptor; Biology; Endocrinology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007770449,0.0001907406,0.0003812083,0.0001441596,0.0001341409,0.00001982674,0.0001430086,0.0001081812,0.00002643178],"category_scores_gemma":[0.000005735018,0.0001095053,0.00006711986,0.0001519719,0.0003187906,0.0001404301,0.00001822523,0.0004083896,3.175933e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004014727,"about_ca_system_score_gemma":0.00003689602,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007252814,"about_ca_topic_score_gemma":0.000001594597,"domain_scores_codex":[0.9986491,0.0002145282,0.0004381216,0.0001548511,0.0003073283,0.0002360412],"domain_scores_gemma":[0.9993312,0.0002453725,0.0002111482,0.00008722838,0.00005745324,0.00006763167],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000471203,0.0005708326,0.003066937,0.0000377868,0.0001640455,0.00002501007,0.01508721,0.000001768085,0.974163,0.00003057369,0.003589912,0.002791719],"study_design_scores_gemma":[0.005965167,0.003068737,0.05108847,0.000050099,0.0002928728,0.0002991091,0.01497151,0.0001326224,0.9216732,0.00005505054,0.002270426,0.0001327181],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9686811,0.02578294,0.00001498379,0.004971726,0.0001231609,0.0003316308,0.000008789335,0.000003470952,0.00008222467],"genre_scores_gemma":[0.9921781,0.00497148,0.00008866903,0.002558065,0.0001041145,0.000007782425,0.000004379663,0.000009720476,0.00007768533],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05248979,"threshold_uncertainty_score":0.4465498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01907350962570026,"score_gpt":0.3304432766112943,"score_spread":0.311369766985594,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}