{"id":"W2162761364","doi":"10.18433/j3ts3g","title":"Smart Polymeric Nanofibers for Topical Delivery of Levothyroxine","year":2010,"lang":"en","type":"article","venue":"Journal of Pharmacy & Pharmaceutical Sciences","topic":"Electrospun Nanofibers in Biomedical Applications","field":"Materials Science","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Nanofiber; Permeation; Materials science; Fourier transform infrared spectroscopy; Drug delivery; Polyvinyl alcohol; Human skin; Penetration (warfare); Transdermal; Biomedical engineering; Vinyl alcohol; Nanotechnology; Chemical engineering; Chemistry; Membrane; Pharmacology; Medicine; Composite material; Polymer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001426042,0.000183875,0.0001058856,0.0002274201,0.0001009236,0.0001105702,0.00009453065,0.000258269,0.0004735595],"category_scores_gemma":[0.0001495807,0.00008544863,0.0001541936,0.00006347793,0.0001000356,0.0003148688,0.00009573535,0.0001889592,0.0001367374],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001146534,"about_ca_system_score_gemma":0.00007445342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001594127,"about_ca_topic_score_gemma":0.0003912003,"domain_scores_codex":[0.9999473,0.000008220975,0.00000531761,0.00001043145,0.0000217145,0.000006970141],"domain_scores_gemma":[0.9999195,0.00001852934,0.0000340774,0.000004006709,0.00001298587,0.00001088578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002698224,0.00001165466,0.00004242551,0.00004717379,0.000003414727,0.00004805542,0.000006900063,0.0001343265,0.9956605,0.0000557086,0.00002206157,0.003940905],"study_design_scores_gemma":[0.0000208481,0.0004656025,0.001092383,0.00001297135,0.00001784382,0.0003222318,0.00001819394,0.001998055,0.9931267,0.00006635021,0.002850426,0.000008339043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804098,0.005710899,0.01205082,0.0001362293,0.00006410415,0.00005663455,0.00007227715,0.0000870527,0.001412233],"genre_scores_gemma":[0.9799177,0.002650651,0.01528904,0.00006143066,0.00003689354,0.00005290979,0.00007638545,0.00001507065,0.001899833],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004735595,"threshold_uncertainty_score":0.001584232,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03769581386767244,"score_gpt":0.3757403820279518,"score_spread":0.3380445681602793,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}