{"id":"W2162763925","doi":"10.1186/1476-4598-9-11","title":"MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells","year":2010,"lang":"en","type":"article","venue":"Molecular Cancer","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":209,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"School of Medicine and Public Health, University of Wisconsin-Madison; National Institutes of Health; National Cancer Institute; Ovarian Cancer Research Fund; U.S. Department of Defense","keywords":"Biology; Immunological synapse; Immune system; Cancer research; Synapse formation; Ovarian tumor; Cell biology; Immunology; Synapse; Ovarian cancer; Neuroscience; T cell; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001274414,0.0002602214,0.0002306081,0.00009767246,0.00008212832,0.0002539733,0.0002095486,0.0002138021,0.001656053],"category_scores_gemma":[0.0001706147,0.00008711885,0.0002040523,0.00007126159,0.0001621523,0.0002112677,0.0003219862,0.0004632703,0.000318838],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000228513,"about_ca_system_score_gemma":0.0002183863,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002789044,"about_ca_topic_score_gemma":0.0004206245,"domain_scores_codex":[0.9998707,0.00002117868,0.00001939158,0.00002090196,0.00002682001,0.00004096367],"domain_scores_gemma":[0.9998658,0.00002089508,0.00004704465,0.00002080268,0.00001330931,0.00003204594],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001930225,0.0000361286,0.0006321986,0.00007547022,0.000008258495,0.00003214037,0.00001355831,0.00006358892,0.9964589,0.0000698648,0.00002873602,0.002388036],"study_design_scores_gemma":[0.00004836722,0.001052348,0.008387104,0.00001357924,0.00002160557,0.0004279799,0.00002841457,0.0007746523,0.9867771,0.00004363913,0.002421344,0.00000387818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971539,0.001156658,0.0007988897,0.00004559533,0.00001293786,0.0000177111,0.00007529352,0.00003504524,0.000703893],"genre_scores_gemma":[0.9979406,0.0003243714,0.0007745725,0.00001804755,0.000004636499,0.00001815649,0.0001163396,0.0000069721,0.0007962036],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001656053,"threshold_uncertainty_score":0.005540073,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006480278014997862,"score_gpt":0.2126010895290136,"score_spread":0.2061208115140157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}