{"id":"W2162763925","doi":"10.1186/1476-4598-9-11","title":"MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells","year":2010,"lang":"en","type":"article","venue":"Molecular Cancer","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":209,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"School of Medicine and Public Health, University of Wisconsin-Madison; National Institutes of Health; National Cancer Institute; Ovarian Cancer Research Fund; U.S. Department of Defense","keywords":"Biology; Immunological synapse; Immune system; Cancer research; Synapse formation; Ovarian tumor; Cell biology; Immunology; Synapse; Ovarian cancer; Neuroscience; T cell; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001676706,0.0001434881,0.000154562,0.00008150311,0.000214739,0.00004230824,0.00006236845,0.0001671744,0.0004983403],"category_scores_gemma":[0.00004218032,0.0001367378,0.0000536039,0.00008606682,0.00007259959,0.0002913366,0.00004113905,0.0004800186,0.0001121257],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004953241,"about_ca_system_score_gemma":0.00003022082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006877644,"about_ca_topic_score_gemma":0.0000295178,"domain_scores_codex":[0.999185,0.00009031313,0.000258861,0.0002162989,0.00003371159,0.0002158475],"domain_scores_gemma":[0.9995923,0.00001690526,0.0001669422,0.0001326484,0.00007269117,0.00001850778],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005043989,0.00001945725,0.00007026436,0.00003443416,0.00004522302,0.000001210616,0.0001575567,0.000001398318,0.9877819,0.00004361413,0.001630647,0.01016379],"study_design_scores_gemma":[0.0005944571,0.00008014739,0.0003643089,0.00003861425,0.00003344542,0.00003455235,0.00009838738,0.00003576556,0.93819,0.00002152107,0.0603588,0.0001500502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912438,0.001044386,0.004698829,0.0004661445,0.001456711,0.0004797371,0.00001433427,0.00009115219,0.0005049459],"genre_scores_gemma":[0.9977239,0.00002743613,0.00005128653,0.0002090621,0.00004540382,0.0001316605,0.0001250632,0.0000197889,0.001666351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05872815,"threshold_uncertainty_score":0.5576007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006480278014997862,"score_gpt":0.2126010895290136,"score_spread":0.2061208115140157,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}