{"id":"W2162766966","doi":"10.1056/nejmoa043335","title":"Natalizumab Induction and Maintenance Therapy for Crohn's Disease","year":2005,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Polyomavirus and related diseases","field":"Medicine","cited_by":926,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Western University; St. Paul's Hospital; University of British Columbia","funders":"National Center for Research Resources","keywords":"Natalizumab; Medicine; Placebo; Internal medicine; Crohn's disease; Adverse effect; Gastroenterology; Clinical trial; Randomized controlled trial; Surgery; Immunology; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0014759,0.0003085571,0.001301537,0.0002997749,0.0002334611,0.0003600743,0.0005628073,0.0005656939,0.002406319],"category_scores_gemma":[0.001227065,0.0001422402,0.0006207476,0.0003292459,0.0003884349,0.0003155043,0.0002228566,0.001353654,0.0003507914],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000490965,"about_ca_system_score_gemma":0.0006205835,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003344361,"about_ca_topic_score_gemma":0.0008944239,"domain_scores_codex":[0.9993356,0.0002587492,0.0001020958,0.0000895959,0.0001222071,0.00009168686],"domain_scores_gemma":[0.9991388,0.0002670903,0.0003166843,0.0000601017,0.00004844863,0.0001688105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.4117051,0.009963833,0.01310634,0.004892661,0.001731802,0.000237307,0.0002152945,0.0007016388,0.02343247,0.0004954648,0.002903158,0.530615],"study_design_scores_gemma":[0.549981,0.3472849,0.0681123,0.001117568,0.002555693,0.001361679,0.00007047375,0.001250829,0.01061442,0.0003994509,0.0171972,0.00005445281],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9198691,0.07315235,0.001110466,0.0009068828,0.0003808103,0.00117169,0.0004200074,0.0001015144,0.002887112],"genre_scores_gemma":[0.9816867,0.01232235,0.0020253,0.000615048,0.0003795229,0.001233434,0.0006272796,0.00001159139,0.001098713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002406319,"threshold_uncertainty_score":0.008049965,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01947213667905243,"score_gpt":0.2934343182490907,"score_spread":0.2739621815700383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}