{"id":"W2162766966","doi":"10.1056/nejmoa043335","title":"Natalizumab Induction and Maintenance Therapy for Crohn's Disease","year":2005,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Polyomavirus and related diseases","field":"Medicine","cited_by":926,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Western University; St. Paul's Hospital; University of British Columbia","funders":"National Center for Research Resources","keywords":"Natalizumab; Medicine; Placebo; Internal medicine; Crohn's disease; Adverse effect; Gastroenterology; Clinical trial; Randomized controlled trial; Surgery; Immunology; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002727973,0.0001088477,0.0002823577,0.0001283191,0.00005058187,0.000006333341,0.00004589239,0.00004845056,0.000102079],"category_scores_gemma":[0.0003155488,0.00005993605,0.00006930542,0.0000718852,0.0001010767,0.0001048033,0.000005842755,0.0001767007,0.000001198976],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003325897,"about_ca_system_score_gemma":0.0001773205,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001734516,"about_ca_topic_score_gemma":0.000002456599,"domain_scores_codex":[0.999184,0.00002127454,0.0003097967,0.00009872473,0.0002371122,0.0001491311],"domain_scores_gemma":[0.9989614,0.0000774328,0.0001741905,0.00009418202,0.0001433888,0.0005493867],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0115453,0.0001598603,0.00249695,0.00005218989,0.0001686855,0.0003902853,0.0004128364,0.00001694546,0.001810014,0.000356286,0.03790037,0.9446903],"study_design_scores_gemma":[0.1593144,0.002445594,0.148004,0.00106785,0.0005444309,0.002456888,0.0001546745,0.0002528552,0.0003762439,0.00185436,0.6833732,0.0001555462],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9179164,0.03826948,0.0007622342,0.04187816,0.00050983,0.0002626924,0.000007012457,0.00001475875,0.0003794862],"genre_scores_gemma":[0.9831401,0.007074936,0.0004849382,0.001517795,0.006608703,0.000001932649,0.000006243515,0.00001475228,0.00115056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9445347,"threshold_uncertainty_score":0.2444121,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01947213667905243,"score_gpt":0.2934343182490907,"score_spread":0.2739621815700383,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}