{"id":"W2162768252","doi":"10.1002/hep.27991","title":"Depletion of B cells induces remission of autoimmune hepatitis in mice through reduced antigen presentation and help to T cells","year":2015,"lang":"en","type":"article","venue":"Hepatology","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Liver Foundation","keywords":"Immunology; Antigen; B cell; Autoimmune hepatitis; Antibody; CD8; Autoantibody; T cell; CD20; Medicine; Biology; Hepatitis; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002683907,0.0008370381,0.0004507195,0.0005353617,0.000221828,0.0003123078,0.0004128688,0.0005519124,0.001692436],"category_scores_gemma":[0.0001328197,0.000217692,0.0003033807,0.0001851652,0.0003771786,0.0002838203,0.0002487141,0.00139701,0.0007509832],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002222694,"about_ca_system_score_gemma":0.0002216468,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002148168,"about_ca_topic_score_gemma":0.0003714235,"domain_scores_codex":[0.9996934,0.00004972105,0.00004047053,0.00005408422,0.00007360457,0.00008867778],"domain_scores_gemma":[0.9996765,0.00003935991,0.0001207397,0.00003208898,0.00002772376,0.0001036058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005247219,0.0001777389,0.0002111224,0.00008409179,0.000009968178,0.00004809947,0.0000165518,0.0000411997,0.9967691,0.00004528104,0.00005764148,0.002014536],"study_design_scores_gemma":[0.0002069972,0.002439009,0.00311794,0.00002670355,0.00003458033,0.0003105331,0.00002853899,0.0003843447,0.9905869,0.00005374654,0.002804134,0.000006504582],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885145,0.00560219,0.002797478,0.0002598749,0.00008801903,0.00008710972,0.0005173903,0.0003937355,0.001739841],"genre_scores_gemma":[0.9890699,0.002343811,0.00333205,0.0002677772,0.00007295378,0.000181127,0.0009284324,0.00008891671,0.003714963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001692436,"threshold_uncertainty_score":0.005661786,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03998363757799869,"score_gpt":0.3077875830168331,"score_spread":0.2678039454388345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}