{"id":"W2162768252","doi":"10.1002/hep.27991","title":"Depletion of B cells induces remission of autoimmune hepatitis in mice through reduced antigen presentation and help to T cells","year":2015,"lang":"en","type":"article","venue":"Hepatology","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":93,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier Universitaire Sainte-Justine","funders":"Canadian Liver Foundation","keywords":"Immunology; Antigen; B cell; Autoimmune hepatitis; Antibody; CD8; Autoantibody; T cell; CD20; Medicine; Biology; Hepatitis; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001418709,0.00008053452,0.0003134634,0.00009718986,0.00001564462,0.00000232923,0.00005567688,0.00009930511,0.00002938258],"category_scores_gemma":[0.0000874398,0.00007478375,0.00002931179,0.0001791648,0.00006505045,0.00008310857,0.00006350063,0.00007991043,0.000005143745],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003327937,"about_ca_system_score_gemma":0.0001158787,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008604954,"about_ca_topic_score_gemma":0.00005102933,"domain_scores_codex":[0.9991458,0.0001368951,0.0003116572,0.0001509514,0.0001242554,0.0001304367],"domain_scores_gemma":[0.9994364,0.00004890397,0.000128446,0.0001737803,0.000134422,0.00007806403],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002837231,0.0001456856,0.3426604,0.0001106286,0.00001488873,0.00000795929,0.001917165,0.000003096201,0.6534508,0.000030745,0.0006613482,0.0007136047],"study_design_scores_gemma":[0.000986248,0.000402527,0.3594843,0.0001223041,0.00002996595,0.00001172209,0.0004807157,0.0002870531,0.6376107,0.0001292698,0.0003925689,0.00006253718],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979922,0.0006294856,0.00005871521,0.0004034416,0.0001649013,0.0003324999,0.00001114869,0.00001058379,0.0003969858],"genre_scores_gemma":[0.997941,0.0006944428,0.001137253,0.00009669836,0.00001536765,0.000006443129,0.0000276497,0.000008469395,0.00007274351],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01682396,"threshold_uncertainty_score":0.9979968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03998363757799869,"score_gpt":0.3077875830168331,"score_spread":0.2678039454388345,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}