{"id":"W2162792820","doi":"10.1093/molehr/gau020","title":"Activation of endocrine-related gene expression in placental choriocarcinoma cell lines following DNA methylation knock-down","year":2014,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"DNA methylation; Biology; Epigenetics; Methylation; Molecular biology; Gene expression; Regulation of gene expression; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002469403,0.0002601529,0.000325131,0.0002757007,0.0001657433,0.0003851332,0.0001588242,0.0001817214,0.001621779],"category_scores_gemma":[0.0002272783,0.0001866387,0.0002523921,0.0003825329,0.0002700007,0.0001146494,0.0001729196,0.0006324442,0.0004686087],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002394292,"about_ca_system_score_gemma":0.0002436634,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002067059,"about_ca_topic_score_gemma":0.002771366,"domain_scores_codex":[0.9997268,0.00002947362,0.00002868958,0.0000701497,0.00009471524,0.00005000924],"domain_scores_gemma":[0.9998069,0.000057887,0.00003052412,0.00003799886,0.0000408083,0.00002595656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005324077,0.00001166247,0.0002183317,0.00002856192,0.000004745335,0.00003660301,0.00003599239,0.00003604629,0.9988903,0.00002565533,0.0000316986,0.0006271324],"study_design_scores_gemma":[0.00001704994,0.0002673021,0.009106369,0.000007340898,0.00002351026,0.0002154979,0.00008466619,0.0008264093,0.985837,0.00003159138,0.003577423,0.000005881865],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845321,0.002637746,0.007660628,0.0001548828,0.00006882704,0.0001193296,0.002277562,0.000225033,0.002324126],"genre_scores_gemma":[0.9772795,0.002254572,0.008664296,0.0001155174,0.00001331127,0.000263847,0.003876515,0.00006847089,0.007463969],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002067059,"threshold_uncertainty_score":0.005425394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008303795739993706,"score_gpt":0.2485097437510139,"score_spread":0.2402059480110202,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}