{"id":"W2162868329","doi":"10.1053/j.gastro.2006.06.098","title":"Adalimumab Induces and Maintains Clinical Response and Remission in Patients With Active Crohn’s Disease: Results of the CHARM Trial","year":2006,"lang":"en","type":"article","venue":"Gastroenterology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary; St. Paul's Hospital; University of British Columbia","funders":"","keywords":"Medicine; Adalimumab; Internal medicine; Placebo; Maintenance therapy; Rheumatoid arthritis; Gastroenterology; Psoriasis; Psoriatic arthritis; Crohn's disease; Clinical trial; Surgery; Disease; Immunology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003142976,0.000899287,0.00312861,0.0003364737,0.0006483967,0.001377304,0.0005199334,0.00103955,0.001363664],"category_scores_gemma":[0.0027045,0.0003840297,0.001743899,0.0004052942,0.0009132709,0.0009398234,0.0004417883,0.002801327,0.0004295116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001100467,"about_ca_system_score_gemma":0.0008257788,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007170243,"about_ca_topic_score_gemma":0.001603059,"domain_scores_codex":[0.9989051,0.0005710752,0.00006725115,0.0001183072,0.0001345317,0.0002037505],"domain_scores_gemma":[0.9979895,0.0006958924,0.0004029476,0.0002342616,0.000109231,0.0005681983],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8942453,0.004776663,0.009641357,0.0007219211,0.002801229,0.0001614333,0.0001303364,0.0009735851,0.00424523,0.0002287548,0.004031131,0.07804305],"study_design_scores_gemma":[0.7887,0.1165904,0.07886893,0.000163778,0.003666837,0.0006488559,0.0001242317,0.001733466,0.002226032,0.0007030477,0.006466784,0.0001076774],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895778,0.006507971,0.000138017,0.0009897243,0.0002400257,0.0001344549,0.0004623327,0.00006987652,0.001879829],"genre_scores_gemma":[0.9945187,0.001783922,0.0004320125,0.0008877231,0.0004798157,0.0001667143,0.0007509709,0.00002092496,0.0009592106],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003142976,"threshold_uncertainty_score":0.01662189,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006034884309255874,"score_gpt":0.2411908001471139,"score_spread":0.2351559158378581,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}