{"id":"W2162877523","doi":"10.1136/gutjnl-2013-304907.508","title":"PTH-020 Factors Influencing Abnormal Gland Morphogenesis in Colorectal Cancer (CRC) - Translational Studies","year":2013,"lang":"en","type":"article","venue":"Gut","topic":"PI3K/AKT/mTOR signaling in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"CDC42; Morphogenesis; Guanine nucleotide exchange factor; Cell biology; Biology; PTEN; Kinase; PI3K/AKT/mTOR pathway; GTPase; Signal transduction; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002078405,0.0002222697,0.0002133291,0.0004255897,0.0002268268,0.0004061303,0.000167258,0.000237762,0.004892607],"category_scores_gemma":[0.0001678793,0.0001326614,0.000308202,0.0004214833,0.0003230076,0.0001850363,0.000202618,0.0004951634,0.001014536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004045752,"about_ca_system_score_gemma":0.0003044908,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001606341,"about_ca_topic_score_gemma":0.001439874,"domain_scores_codex":[0.9998662,0.00001776151,0.00001105641,0.00002894813,0.00004059195,0.00003529018],"domain_scores_gemma":[0.9998534,0.00001870274,0.0000397903,0.00001536521,0.00001766243,0.0000550292],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003480607,0.00002999887,0.0007312016,0.00007278343,0.000006360594,0.0001836606,0.00001983827,0.00003279298,0.9961742,0.0000926599,0.0001264208,0.002182028],"study_design_scores_gemma":[0.00007545297,0.001645238,0.07813966,0.00001740078,0.00008087412,0.002500059,0.0001807047,0.0005958643,0.8941074,0.0001884358,0.02244977,0.00001904868],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9856343,0.004116585,0.002582036,0.0002786183,0.00007462339,0.000109716,0.003038475,0.0001713354,0.003994459],"genre_scores_gemma":[0.98382,0.002340267,0.002158918,0.0001133209,0.00002919386,0.0001110639,0.003966303,0.00005566831,0.007405268],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004892607,"threshold_uncertainty_score":0.01636744,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02180169114773206,"score_gpt":0.2865746483593511,"score_spread":0.2647729572116191,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}