{"id":"W2162895414","doi":"10.1128/aac.00322-11","title":"Antimicrobial Properties of MX-2401, an Expanded-Spectrum Lipopeptide Active in the Presence of Lung Surfactant","year":2011,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Michael Smith Health Research BC","keywords":"Lipopeptide; Pulmonary surfactant; Antimicrobial; Chemistry; Microbiology; Lung; Medicine; Biology; Bacteria; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000169487,0.0002555104,0.000168145,0.0001637599,0.00007676063,0.0001744452,0.0001111596,0.0002851028,0.0006115466],"category_scores_gemma":[0.0002063505,0.00007330117,0.0001625323,0.00007467669,0.0001105998,0.0001853049,0.0001242358,0.0003214089,0.000236691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001240898,"about_ca_system_score_gemma":0.0001113022,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002645572,"about_ca_topic_score_gemma":0.0001275154,"domain_scores_codex":[0.9999152,0.00002296808,0.000006954986,0.00001395478,0.00002703753,0.00001387567],"domain_scores_gemma":[0.9999123,0.00002135585,0.00001830869,0.000005098814,0.00001638747,0.00002656309],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002817337,0.00003077034,0.0001676062,0.00004469474,0.000003377323,0.00003392468,0.000008332508,0.00006788286,0.996087,0.00002431786,0.00003185057,0.003218569],"study_design_scores_gemma":[0.00003918459,0.003541105,0.004672343,0.00001190238,0.00001719761,0.0004574392,0.00001574911,0.0007561893,0.9875069,0.00001835311,0.002955523,0.000008189244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9909493,0.006979357,0.0006725725,0.00004862767,0.00002193309,0.00002209121,0.0002319529,0.00002486464,0.001049237],"genre_scores_gemma":[0.9946998,0.002399961,0.001044,0.00004410544,0.00001691495,0.00001467028,0.0004524189,0.00000613104,0.001321954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006115466,"threshold_uncertainty_score":0.00204581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02707404822961504,"score_gpt":0.2340786156232105,"score_spread":0.2070045673935955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}