{"id":"W2163081237","doi":"10.2337/db07-1608","title":"<i>Slc11a1</i>Enhances the Autoimmune Diabetogenic T-Cell Response by Altering Processing and Presentation of Pancreatic Islet Antigens","year":2008,"lang":"en","type":"article","venue":"Diabetes","topic":"Diabetes and associated disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; Wellcome Trust","keywords":"Antigen presentation; Biology; NOD mice; Immunology; Major histocompatibility complex; Antigen; Immune system; Antigen-presenting cell; Antigen processing; Pancreatic islets; T cell; Cell biology; Islet; Autoimmunity; Endocrinology; Diabetes mellitus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001224121,0.0003596199,0.0002309612,0.000169001,0.0001087114,0.000265811,0.0001363476,0.0002874674,0.002151677],"category_scores_gemma":[0.0001017188,0.00009444514,0.0002100889,0.00009570962,0.0002668906,0.000154176,0.0001385187,0.0003760877,0.000408383],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002494841,"about_ca_system_score_gemma":0.00009280353,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002631691,"about_ca_topic_score_gemma":0.0003829433,"domain_scores_codex":[0.9998438,0.00003072013,0.00001668696,0.00003277128,0.00003405325,0.00004185399],"domain_scores_gemma":[0.9997709,0.00003174604,0.00009108895,0.00001713734,0.00001821343,0.00007085314],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002234348,0.00003259503,0.0005673038,0.0000334112,0.000006546792,0.00008156754,0.000005012381,0.00001932936,0.9983463,0.0000426404,0.00004352692,0.0005982875],"study_design_scores_gemma":[0.00007187758,0.0009139889,0.01992711,0.00001467866,0.00005965031,0.001677457,0.00004728047,0.0007778598,0.9741637,0.00007351689,0.002265093,0.000007748785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978384,0.0004983371,0.0005581938,0.0001301873,0.00002159267,0.000007985876,0.0001680215,0.00006220229,0.0007149883],"genre_scores_gemma":[0.9975775,0.0003217533,0.0006916572,0.00009546996,0.0000228674,0.00001560549,0.0002583928,0.00002739353,0.0009894639],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002151677,"threshold_uncertainty_score":0.007198036,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005447757325726001,"score_gpt":0.2153086472016277,"score_spread":0.2098608898759017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}