{"id":"W2163123363","doi":"10.1200/jco.2005.09.133","title":"Phase III Randomized Multicenter Study of a Humanized Anti-CD33 Monoclonal Antibody, Lintuzumab, in Combination With Chemotherapy, Versus Chemotherapy Alone in Patients With Refractory or First-Relapsed Acute Myeloid Leukemia","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":249,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Medicine; Internal medicine; Chemotherapy; Cytarabine; Gastroenterology; Etoposide; Induction chemotherapy; Mitoxantrone; Chills; CD33; Refractory (planetary science); Chemotherapy regimen; Surgery; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005047583,0.0003877085,0.004512969,0.0007205759,0.00005320824,0.00001570366,0.0003994564,0.0005150393,0.0002610913],"category_scores_gemma":[0.001522099,0.0002322894,0.0003407313,0.0005746804,0.0005427134,0.0003624834,0.00006658578,0.002223379,0.000005501581],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001906548,"about_ca_system_score_gemma":0.002995829,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002060907,"about_ca_topic_score_gemma":0.0007903387,"domain_scores_codex":[0.9926005,0.001142875,0.004145297,0.0004606356,0.00115339,0.0004973249],"domain_scores_gemma":[0.9912093,0.003900321,0.003088573,0.0004099001,0.001061922,0.0003300181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.856476,0.04472093,0.06977241,0.00003386283,0.00208404,0.0005953176,0.001779769,0.00008484589,0.0002228725,0.00000269587,0.0002012567,0.02402601],"study_design_scores_gemma":[0.7625263,0.08067385,0.1521837,0.0002562175,0.0004369463,0.00002222007,0.0003326894,0.002387144,0.0001434745,0.000003076585,0.0008437696,0.0001906373],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940905,0.00005541096,0.0001289226,0.002355107,0.0002568831,0.002970665,0.000004056852,0.0000143763,0.000124085],"genre_scores_gemma":[0.9931631,0.0009205302,0.004617224,0.0007419577,0.0002973711,0.00003338881,0.00002458823,0.00006929159,0.0001325643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09394974,"threshold_uncertainty_score":0.96596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04636817910442764,"score_gpt":0.427938840716764,"score_spread":0.3815706616123364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}