{"id":"W2163123363","doi":"10.1200/jco.2005.09.133","title":"Phase III Randomized Multicenter Study of a Humanized Anti-CD33 Monoclonal Antibody, Lintuzumab, in Combination With Chemotherapy, Versus Chemotherapy Alone in Patients With Refractory or First-Relapsed Acute Myeloid Leukemia","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":249,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"","keywords":"Medicine; Internal medicine; Chemotherapy; Cytarabine; Gastroenterology; Etoposide; Induction chemotherapy; Mitoxantrone; Chills; CD33; Refractory (planetary science); Chemotherapy regimen; Surgery; Oncology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002430886,0.001856255,0.003439374,0.0004764289,0.0004592899,0.001147896,0.001235783,0.001725085,0.005430171],"category_scores_gemma":[0.001820353,0.0007246732,0.001328074,0.0005444519,0.001758573,0.001053088,0.0004784001,0.003521798,0.001035322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001273387,"about_ca_system_score_gemma":0.00171968,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000888278,"about_ca_topic_score_gemma":0.002001843,"domain_scores_codex":[0.9991195,0.0005703039,0.00003596661,0.0001188173,0.00004837451,0.0001071128],"domain_scores_gemma":[0.9983659,0.0003847331,0.0003966499,0.0001255718,0.00007622493,0.0006509113],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9725375,0.01307912,0.0007061854,0.0002067006,0.0005118674,0.00003331134,0.00004403875,0.0003867507,0.002542073,0.00008412428,0.000571065,0.009297158],"study_design_scores_gemma":[0.8863254,0.1108349,0.001256104,0.00001384143,0.0002056939,0.00003812753,0.00001665603,0.0003815722,0.0004229726,0.00007914242,0.0004170487,0.000008542516],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910359,0.00211902,0.0006125041,0.0005962097,0.0004182803,0.003323268,0.0006383604,0.00009102376,0.001165384],"genre_scores_gemma":[0.9869065,0.001638971,0.001657302,0.0009983192,0.0004948321,0.005032454,0.001065726,0.00002921831,0.002176716],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005430171,"threshold_uncertainty_score":0.01816571,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04636817910442764,"score_gpt":0.427938840716764,"score_spread":0.3815706616123364,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}