{"id":"W2163147351","doi":"10.1186/1754-6834-6-139","title":"Manipulating the sleeping beauty mutase operon for the production of 1-propanol in engineered Escherichia coli","year":2013,"lang":"en","type":"article","venue":"Biotechnology for Biofuels","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Operon; Escherichia coli; Biochemistry; Mutase; Biology; Gene; Alcohol dehydrogenase; Metabolic engineering; Recombineering; Chemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003467358,0.0001391634,0.0001478694,0.00006305637,0.00010509,0.00001110174,0.0002444383,0.000298103,0.000002401214],"category_scores_gemma":[0.0005384616,0.0000889769,0.00008100336,0.0001913102,0.0001264166,0.000005819106,0.00006006462,0.0001213386,0.000001414872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001385379,"about_ca_system_score_gemma":0.000021094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007050962,"about_ca_topic_score_gemma":0.00001738176,"domain_scores_codex":[0.9991149,0.00001770748,0.0002577646,0.0003025794,0.00004347559,0.0002635379],"domain_scores_gemma":[0.9993732,0.00001599764,0.0001025369,0.0004182906,0.00007477462,0.00001520426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002810912,0.0000274758,0.0000578625,0.0000618393,0.00003762557,2.944894e-8,0.000023763,0.0004528528,0.9842958,0.0003001167,0.0002319483,0.01448258],"study_design_scores_gemma":[0.0002606476,0.0001606104,0.0009886622,0.00001946943,0.00002481018,0.000005638618,0.0001061797,0.001277702,0.9849167,0.00007395503,0.0120474,0.0001182494],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9816748,0.00135831,0.0111894,0.003271521,0.0006682694,0.001780156,0.00001772576,0.00003700034,0.000002828459],"genre_scores_gemma":[0.9948756,0.0001546245,0.003946891,0.00004614044,0.0003167059,0.0004530494,0.00003440729,0.00002258373,0.0001500434],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01436433,"threshold_uncertainty_score":0.3628373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01214851313890894,"score_gpt":0.2270325506969773,"score_spread":0.2148840375580684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}