{"id":"W2163231305","doi":"10.1189/jlb.0410222","title":"Cytohesin-1 regulates fMLF-mediated activation and functions of the β2 integrin Mac-1 in human neutrophils","year":2011,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Cell Adhesion Molecules Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Centre hospitalier de l'Université Laval","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases; Canadian Institutes of Health Research","keywords":"Biology; Integrin; Cell biology; Neutrophile; Immunology; Integrin alpha M; Downregulation and upregulation; NADPH oxidase; Receptor; Reactive oxygen species; Inflammation; Biochemistry; Gene; Flow cytometry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003731835,0.00009131585,0.0003006854,0.0003429156,0.00003980224,0.000003653666,0.0001302324,0.0001382441,0.0001324367],"category_scores_gemma":[0.0003343586,0.00005447099,0.00008885876,0.000248738,0.000231171,0.0000518829,0.00007143981,0.0003386044,0.000002748686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001046373,"about_ca_system_score_gemma":0.0001632157,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007393469,"about_ca_topic_score_gemma":0.00002297585,"domain_scores_codex":[0.9989295,0.0001836402,0.0004801136,0.0001103973,0.0001356966,0.0001606475],"domain_scores_gemma":[0.9990574,0.0001487773,0.0003233736,0.0001729059,0.0002170622,0.00008045897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004645954,0.0001214313,0.05851656,0.00002157011,0.00004257755,0.00001738161,0.0001951668,0.000001303879,0.9390398,0.0001262003,0.0002504844,0.001202879],"study_design_scores_gemma":[0.0015504,0.0009889025,0.515604,0.0001048773,0.00002975622,0.0001921271,0.0001812463,0.00001929498,0.479454,0.0004829207,0.001341771,0.00005071425],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979903,0.0001782436,0.0000500417,0.0007545967,0.00009037938,0.0001452893,0.000001471821,0.000004033337,0.0007857018],"genre_scores_gemma":[0.999153,0.0001318519,0.0001934555,0.00009472582,0.00008252199,0.000001916629,0.000003500032,0.000009899395,0.000329088],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4595858,"threshold_uncertainty_score":0.2221262,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04706826076064693,"score_gpt":0.3033055596981351,"score_spread":0.2562372989374881,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}