{"id":"W2163252817","doi":"10.1210/en.2011-1590","title":"c-myc and skp2 Coordinate p27 Degradation, Vascular Smooth Muscle Proliferation, and Neointima Formation Induced by the Parathyroid Hormone-Related Protein","year":2011,"lang":"en","type":"article","venue":"Endocrinology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"McGill University; University of Pittsburgh","keywords":"Neointima; Parathyroid hormone-related protein; Gene knockdown; Vascular smooth muscle; Internal medicine; Cell growth; Endocrinology; Chemistry; Cell cycle; Cancer research; Restenosis; Cell biology; Biology; Cell; Parathyroid hormone; Medicine; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007717966,0.000466259,0.0002665406,0.0003244012,0.0001870701,0.0003182555,0.0001633153,0.0002308941,0.000973502],"category_scores_gemma":[0.00009289233,0.0002410332,0.0002158646,0.0002422453,0.0003117607,0.000212201,0.0002584912,0.0004372894,0.0003741079],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004982945,"about_ca_system_score_gemma":0.0003354286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008497431,"about_ca_topic_score_gemma":0.00172531,"domain_scores_codex":[0.9998504,0.00001347795,0.00001194677,0.00003869838,0.00004152887,0.00004405674],"domain_scores_gemma":[0.9998944,0.000009081762,0.00003215916,0.00001120868,0.0000114409,0.00004173047],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002222727,0.00001892968,0.0002137753,0.00002850199,0.000004822823,0.00006503756,0.00000965549,0.0000624513,0.9984708,0.000106681,0.00005174724,0.0007452424],"study_design_scores_gemma":[0.00003709916,0.0002822324,0.01228547,0.000004079469,0.00002022916,0.0005588439,0.00003093407,0.001836482,0.9819005,0.00009207251,0.002946311,0.000005722283],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931424,0.002398178,0.00243965,0.000100646,0.0000290851,0.00002128084,0.0005177252,0.0001232828,0.001227718],"genre_scores_gemma":[0.9907199,0.001184228,0.002083964,0.0000549668,0.00001960048,0.00007663716,0.001082349,0.00003216512,0.004746038],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000973502,"threshold_uncertainty_score":0.003615379,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0180404389040235,"score_gpt":0.2261646058280411,"score_spread":0.2081241669240176,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}