{"id":"W2163255002","doi":"10.2174/1566524033479500","title":"The Quest for a Tumor Suppressor Gene Phenotype","year":2003,"lang":"en","type":"review","venue":"Current Molecular Medicine","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal General Hospital; McGill University Health Centre","funders":"","keywords":"Phenotype; Suppressor; Gene; Tumor suppressor gene; Cancer research; Genetics; Biology; Computational biology; Carcinogenesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005556957,0.0002853435,0.0005727349,0.0006229776,0.0002001586,0.001122972,0.0005226797,0.0009838847,0.001601211],"category_scores_gemma":[0.0006030518,0.0001387267,0.0002282069,0.0002908294,0.001281926,0.001167282,0.0005218327,0.001664343,0.001489035],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004182952,"about_ca_system_score_gemma":0.0005797178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001682551,"about_ca_topic_score_gemma":0.00016387,"domain_scores_codex":[0.9997273,0.00004140114,0.00002494729,0.00007925163,0.0001030019,0.00002419137],"domain_scores_gemma":[0.9995788,0.0001579912,0.00007619347,0.00004641747,0.00009899203,0.00004162133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009885343,0.00007817258,0.002431555,0.001600425,0.00004394956,0.002229634,0.0003929638,0.0003303644,0.7179324,0.09247065,0.005053908,0.177337],"study_design_scores_gemma":[0.00002741054,0.000771285,0.003843115,0.000356043,0.0001047427,0.01698916,0.0005402152,0.0007996188,0.3435926,0.03131393,0.6016129,0.00004882595],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.320462,0.407987,0.1549842,0.03839866,0.00258203,0.0002111561,0.001234119,0.001854979,0.07228581],"genre_scores_gemma":[0.6463823,0.2388103,0.05143463,0.01704859,0.001546373,0.0002467141,0.001388879,0.0003241498,0.042818],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001601211,"threshold_uncertainty_score":0.00535661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04604771245854063,"score_gpt":0.375060095789978,"score_spread":0.3290123833314373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}