{"id":"W2163255002","doi":"10.2174/1566524033479500","title":"The Quest for a Tumor Suppressor Gene Phenotype","year":2003,"lang":"en","type":"review","venue":"Current Molecular Medicine","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Montreal General Hospital; McGill University Health Centre","funders":"","keywords":"Phenotype; Suppressor; Gene; Tumor suppressor gene; Cancer research; Genetics; Biology; Computational biology; Carcinogenesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006514862,0.0004861355,0.0008094977,0.00006960301,0.0001874575,0.00003088343,0.0004612871,0.0002241861,0.00001108728],"category_scores_gemma":[0.000626252,0.0003064406,0.00042232,0.000157188,0.0001892606,0.000001325766,0.0000949744,0.0002370835,0.00001153067],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003175591,"about_ca_system_score_gemma":0.0002686598,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001942504,"about_ca_topic_score_gemma":0.000002406982,"domain_scores_codex":[0.997735,0.0002581106,0.0006516299,0.000651047,0.0002691815,0.0004350357],"domain_scores_gemma":[0.9982669,0.0000951973,0.0004017275,0.0008684015,0.000207505,0.0001602372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002098045,0.00006451805,8.196921e-7,0.003682079,0.0002422686,0.000005689231,0.00001279816,0.000002611167,0.0111125,0.0008110944,0.004400328,0.9796443],"study_design_scores_gemma":[0.0004319748,0.0002824774,5.121516e-7,0.001263378,0.0006582899,0.000008120326,0.000003323265,0.000004922806,0.003310785,0.0002302239,0.9934707,0.0003353452],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00002335972,0.9857023,0.01057066,0.00006188846,0.001827831,0.001402375,0.00006382631,0.00001150695,0.000336216],"genre_scores_gemma":[0.00002689504,0.9961264,0.0003217259,0.00006506731,0.0010312,0.0004617247,0.00162218,0.0001049673,0.0002398603],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9890703,"threshold_uncertainty_score":0.9999388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04604771245854063,"score_gpt":0.375060095789978,"score_spread":0.3290123833314373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}