{"id":"W2163291758","doi":"10.1128/jb.00201-10","title":"The Rut Pathway for Pyrimidine Degradation: Novel Chemistry and Toxicity Problems","year":2010,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"IONICS Mass Spectrometry (Canada)","funders":"Institute of Genetics; National Center for Research Resources; National Institute of General Medical Sciences; National Science Foundation; National Institutes of Health; Keio University; Washington State University","keywords":"Chemistry; Stereochemistry; Hydrolysis; Uracil; Yield (engineering); Pyrimidine; Organic chemistry; Biochemistry; DNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007853037,0.0006099824,0.0008191453,0.0005139016,0.0003335171,0.001195943,0.0008260817,0.001296616,0.0009267004],"category_scores_gemma":[0.000497191,0.0003066454,0.0004923637,0.0003071926,0.0008804963,0.002994184,0.0006138284,0.001679518,0.0006249466],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007989994,"about_ca_system_score_gemma":0.0004736323,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002104173,"about_ca_topic_score_gemma":0.0001877639,"domain_scores_codex":[0.9996289,0.00008892035,0.00002912294,0.0000774399,0.0001106368,0.0000650802],"domain_scores_gemma":[0.9996045,0.0001201116,0.00005986891,0.00008119483,0.00006909769,0.00006530106],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004800842,0.0002174468,0.002049757,0.001033231,0.00005677628,0.00171063,0.0001643782,0.003168501,0.8523911,0.03577925,0.001315313,0.1016335],"study_design_scores_gemma":[0.00007762053,0.002071569,0.005225813,0.0001525158,0.00007778548,0.01076894,0.0003158426,0.02059815,0.7778891,0.08156336,0.1011289,0.0001303422],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5461664,0.1881878,0.2304827,0.01538118,0.0007235107,0.0002118645,0.0005110667,0.001607476,0.01672797],"genre_scores_gemma":[0.8913903,0.05265724,0.04620698,0.001016152,0.0003533621,0.0001098037,0.0006097317,0.0001410601,0.007515518],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001296616,"threshold_uncertainty_score":0.005797207,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01315748386324916,"score_gpt":0.2286116217050472,"score_spread":0.215454137841798,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}