{"id":"W2163303312","doi":"10.1371/journal.ppat.1002619","title":"The Role of Mast Cells in the Defence against Pathogens","year":2012,"lang":"en","type":"review","venue":"PLoS Pathogens","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":204,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Degranulation; Chymase; Cell biology; Tryptase; Prostaglandin D2; Stem cell factor; Chemokine; Histamine; Interleukin 33; Biology; Mast cell; Immunology; Cytokine; Progenitor cell; Haematopoiesis; Tumor necrosis factor alpha; Inflammation; Stem cell; Interleukin; Prostaglandin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007950247,0.0009718706,0.001316901,0.001462058,0.000311819,0.0009953717,0.001163386,0.001290213,0.002453983],"category_scores_gemma":[0.0007062064,0.0002719103,0.0003417133,0.001762834,0.0007234439,0.001850547,0.0009341292,0.001988959,0.002065178],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006290048,"about_ca_system_score_gemma":0.0008274525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006520887,"about_ca_topic_score_gemma":0.00104369,"domain_scores_codex":[0.9997917,0.00003129979,0.00002642396,0.0000371205,0.00008622178,0.00002727372],"domain_scores_gemma":[0.9996537,0.0001451576,0.00004862406,0.00001274203,0.00008764218,0.00005224597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001276351,0.00004972514,0.0001749712,0.01090103,0.00006641552,0.0003556772,0.00006872967,0.0003871082,0.003662497,0.004492881,0.04712752,0.9325858],"study_design_scores_gemma":[0.00002395736,0.00009224479,0.0009130035,0.002155874,0.00005860176,0.001552859,0.00007552827,0.00007360479,0.0005275341,0.003422366,0.9910883,0.00001614734],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006924686,0.9987387,0.00009121255,0.000260689,0.0003786546,0.000001724272,0.000006408256,0.000003698345,0.0004496833],"genre_scores_gemma":[0.0004642899,0.9983608,0.00009688336,0.0001172028,0.0004492779,0.000002673334,0.00001093283,8.364804e-7,0.0004971579],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002453983,"threshold_uncertainty_score":0.008209407,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02812537571689807,"score_gpt":0.2370155128961302,"score_spread":0.2088901371792321,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}