{"id":"W2163328503","doi":"10.2353/ajpath.2008.070572","title":"Overexpression of Lymphotoxin in T Cells Induces Fulminant Thymic Involution","year":2008,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"National Institutes of Health; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Universität Zürich; European Commission; Biogen; U.S. Public Health Service; Howard Hughes Medical Institute","keywords":"Lymphotoxin; Biology; Involution (esoterism); Thymic involution; CD8; Stromal cell; Thymocyte; Lymphopoiesis; T cell; Cell biology; Tumor necrosis factor alpha; Receptor; Immunology; Cancer research; Stem cell; Immune system; Haematopoiesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003442513,0.0006838878,0.0004329576,0.0005552444,0.0003199433,0.0007020296,0.0003307182,0.0006979024,0.001686352],"category_scores_gemma":[0.0003485215,0.0002879644,0.0005588244,0.0003524932,0.0004254594,0.0004350037,0.0004597718,0.001695622,0.0006891395],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005916652,"about_ca_system_score_gemma":0.0003629748,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005167358,"about_ca_topic_score_gemma":0.0009517251,"domain_scores_codex":[0.9993647,0.0001169892,0.00009560114,0.00007690315,0.0000939753,0.0002519012],"domain_scores_gemma":[0.9989917,0.0003318176,0.0002055711,0.0001432312,0.00004411136,0.0002836947],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000356288,0.00006157014,0.0002063594,0.00002138575,0.000005322122,0.0001540672,0.00001757097,0.0001037018,0.9984506,0.0001039185,0.00003510819,0.0004840468],"study_design_scores_gemma":[0.00004714688,0.0004109752,0.002203856,0.00000533141,0.00001490095,0.0002595951,0.00004668153,0.0007896803,0.9953839,0.00004552281,0.0007880365,0.000004278959],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958686,0.0009239233,0.001463059,0.0001198205,0.00008452671,0.00003999203,0.0003835138,0.0001295983,0.0009871394],"genre_scores_gemma":[0.9971455,0.0002247061,0.0005758639,0.00003736546,0.00002174756,0.0000352235,0.0003502052,0.0000278804,0.0015814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001686352,"threshold_uncertainty_score":0.00564146,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01143610712634202,"score_gpt":0.2253370120099975,"score_spread":0.2139009048836555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}