{"id":"W2163353462","doi":"10.1016/j.pupt.2014.07.005","title":"Airway smooth muscle in asthma: Linking contraction and mechanotransduction to disease pathogenesis and remodelling","year":2014,"lang":"en","type":"review","venue":"Pulmonary Pharmacology & Therapeutics","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba; Research Manitoba; University of British Columbia","funders":"Medical Research Council; Lung Foundation Netherlands; National Health and Medical Research Council; National Centre for the Replacement Refinement and Reduction of Animals in Research; Ministry of Education, Culture, Sports, Science and Technology; National Centre for the Replacement, Refinement and Reduction of Animals in Research","keywords":"Pathogenesis; Bronchoconstriction; Asthma; Mechanotransduction; Medicine; Contraction (grammar); Immunology; Inflammation; Airway; Immune system; Neuroscience; Biology; Internal medicine; Anesthesia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003530899,0.000472482,0.001196228,0.000392859,0.0001555801,0.00002086859,0.00009013183,0.0003545824,0.00003593438],"category_scores_gemma":[0.000005739428,0.000409084,0.0002070275,0.0002571367,0.0001357442,0.00008681346,0.00005108618,0.0005054719,0.00001006777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001143585,"about_ca_system_score_gemma":0.0002472179,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004119312,"about_ca_topic_score_gemma":0.000002179898,"domain_scores_codex":[0.9977623,0.0004085602,0.0005643493,0.0006875442,0.0001866472,0.0003906024],"domain_scores_gemma":[0.9988301,0.0001854858,0.0002009961,0.0002066186,0.00006329324,0.0005135114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002478154,0.0002256971,0.00009975752,0.005408262,0.00007605478,0.0002264279,0.00005429913,0.00003514024,0.001167286,0.000003986982,0.00000569169,0.9924496],"study_design_scores_gemma":[0.0005534148,0.0001674438,0.0007102742,0.002603429,0.003819545,0.0000932546,0.00002746883,0.001820548,0.00001461518,0.00003583739,0.989776,0.0003781738],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007904,0.9885656,0.0009661908,0.0004178453,0.0005255837,0.001485132,0.0000405732,0.00007118649,0.00002384042],"genre_scores_gemma":[0.01102165,0.9850695,0.0001544266,0.002683947,0.0006607307,0.0001868287,0.00007926997,0.00009688109,0.00004678813],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9920714,"threshold_uncertainty_score":0.9998361,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0420005584082627,"score_gpt":0.343820896443665,"score_spread":0.3018203380354023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}