{"id":"W2163353462","doi":"10.1016/j.pupt.2014.07.005","title":"Airway smooth muscle in asthma: Linking contraction and mechanotransduction to disease pathogenesis and remodelling","year":2014,"lang":"en","type":"review","venue":"Pulmonary Pharmacology & Therapeutics","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba; Research Manitoba; University of British Columbia","funders":"Medical Research Council; Lung Foundation Netherlands; National Health and Medical Research Council; National Centre for the Replacement Refinement and Reduction of Animals in Research; Ministry of Education, Culture, Sports, Science and Technology; National Centre for the Replacement, Refinement and Reduction of Animals in Research","keywords":"Pathogenesis; Bronchoconstriction; Asthma; Mechanotransduction; Medicine; Contraction (grammar); Immunology; Inflammation; Airway; Immune system; Neuroscience; Biology; Internal medicine; Anesthesia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006116742,0.0009289299,0.001749408,0.002338638,0.0002672521,0.001105218,0.000784571,0.001431804,0.003604749],"category_scores_gemma":[0.0005741948,0.0003313816,0.000507941,0.002431116,0.0005787528,0.001376294,0.00124843,0.001920129,0.00174238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004319682,"about_ca_system_score_gemma":0.001371864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009922349,"about_ca_topic_score_gemma":0.002892125,"domain_scores_codex":[0.9997756,0.00003152189,0.0000322101,0.00003598303,0.0000997758,0.00002502007],"domain_scores_gemma":[0.9996283,0.0001599294,0.0000776635,0.00000736666,0.0000825867,0.00004407629],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001116568,0.00009583619,0.0002480585,0.02436325,0.000152153,0.0002214351,0.0000642494,0.0003125113,0.002784719,0.001746952,0.024105,0.9457942],"study_design_scores_gemma":[0.00005945472,0.0001994908,0.002621813,0.008396135,0.0003956886,0.001643131,0.0001488531,0.0001992566,0.0005932426,0.00236591,0.9833326,0.00004439765],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007624719,0.9991376,0.00008369398,0.0002141097,0.0001677674,0.000003472918,0.000009699079,0.000003473004,0.0003038548],"genre_scores_gemma":[0.0004120067,0.9987522,0.000114315,0.0001559213,0.0002616509,0.000003433791,0.00001255836,4.494508e-7,0.0002874353],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003604749,"threshold_uncertainty_score":0.01205903,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0420005584082627,"score_gpt":0.343820896443665,"score_spread":0.3018203380354023,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}