{"id":"W2163410642","doi":"10.4049/jimmunol.0901881","title":"CD39+Foxp3+ Regulatory T Cells Suppress Pathogenic Th17 Cells and Are Impaired in Multiple Sclerosis","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":475,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"Science Foundation Ireland","keywords":"IL-2 receptor; FOXP3; Interleukin-7 receptor; Biology; Immunology; Interleukin 21; Cell biology; T cell; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001089053,0.0003792078,0.0008703586,0.0003767428,0.0003026421,0.00002057096,0.000882372,0.0006383528,0.0002012258],"category_scores_gemma":[0.00008461705,0.0002658874,0.0002209553,0.0002397303,0.0008765764,0.0001935226,0.0002009193,0.00128596,0.0001396776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000090245,"about_ca_system_score_gemma":0.00009844173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008071554,"about_ca_topic_score_gemma":0.00005009241,"domain_scores_codex":[0.9966531,0.001211686,0.001013884,0.0002866803,0.00007303476,0.0007615665],"domain_scores_gemma":[0.9976885,0.0005919295,0.0008977164,0.0006216503,0.000160223,0.00003996575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001195898,0.0003695144,0.0008158239,0.000008819939,0.0002777706,0.00004520053,0.00114626,0.00003819529,0.9905508,0.00004529581,0.001651419,0.003855035],"study_design_scores_gemma":[0.005176233,0.001277912,0.08043552,0.0001204175,0.0001466189,0.001298549,0.001689953,0.000006221002,0.9054227,0.0003862363,0.003720731,0.0003189406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9621112,0.03501126,0.00001923116,0.0009827128,0.001496464,0.0002434237,0.00002222934,0.00003314098,0.00008028302],"genre_scores_gemma":[0.9936953,0.005079553,0.00007318043,0.000416439,0.00006052543,0.00000353,0.000005861072,0.00002700004,0.0006386538],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08512811,"threshold_uncertainty_score":0.9999793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01720097625021615,"score_gpt":0.1994192173469574,"score_spread":0.1822182410967413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}