{"id":"W2163432283","doi":"10.1002/ejoc.201402038","title":"Catalyst‐Free One‐Pot Tandem Reduction of Oxo and Ene/Yne Functionalities by Hydrazine: Synthesis of Substituted Oxindoles from Isatins","year":2014,"lang":"en","type":"article","venue":"European Journal of Organic Chemistry","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nipissing University","funders":"","keywords":"Chemistry; Hydrazine (antidepressant); Catalysis; Hydrate; Oxindole; Tandem; Ene reaction; Combinatorial chemistry; Organic chemistry; Cascade reaction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000989594,0.0002416103,0.0005271464,0.00005731412,0.00007450161,0.00002897774,0.0003982043,0.00009425171,0.003505207],"category_scores_gemma":[0.002799216,0.0002491373,0.0001573472,0.0001980386,0.0002831302,0.0001775403,0.0001287175,0.0002952168,0.000003793355],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001032053,"about_ca_system_score_gemma":0.0001364935,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002240817,"about_ca_topic_score_gemma":0.000001900857,"domain_scores_codex":[0.9976913,0.0001374721,0.001145605,0.0002804643,0.0005834394,0.0001616958],"domain_scores_gemma":[0.9970329,0.0005117788,0.001342783,0.0005284215,0.0004264466,0.0001576564],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009624891,0.0001381731,0.001053939,0.0002728569,0.0002945285,0.000003985487,0.0001651167,0.00003130156,0.9937677,0.00001898,0.002869471,0.001287655],"study_design_scores_gemma":[0.001186871,0.00002061913,0.001822249,0.0003540179,0.0002904177,0.0001780519,0.0005475553,0.00002472369,0.9913132,0.0001953624,0.003855512,0.0002114521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9836375,0.0008235285,0.005238338,0.0002491169,0.0001842211,0.00002908418,0.0001972775,0.0000321532,0.009608835],"genre_scores_gemma":[0.9958001,0.00013536,0.001905572,0.00001585816,0.0006919067,8.174088e-7,0.000129497,0.00006024819,0.001260597],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0121627,"threshold_uncertainty_score":0.9999961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01356506141339224,"score_gpt":0.208673799608074,"score_spread":0.1951087381946818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}