{"id":"W2163443690","doi":"10.1373/clinchem.2007.101949","title":"Combined Newborn Screening for Succinylacetone, Amino Acids, and Acylcarnitines in Dried Blood Spots","year":2008,"lang":"en","type":"article","venue":"Clinical Chemistry","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":142,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"University of Washington; Cincinnati Children's Hospital Medical Center","keywords":"Newborn screening; Chemistry; Chromatography; Dried blood; Tandem mass spectrometry; Spots; Amino acid; Amino acid analysis; Tyrosine; Mass spectrometry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000551677,0.0005866597,0.0005357997,0.001236397,0.0003198833,0.0004235396,0.000324456,0.0003546381,0.0007109166],"category_scores_gemma":[0.0007977491,0.0001790789,0.0002241491,0.0006105929,0.000317425,0.000189497,0.0004015966,0.0004131812,0.0002684071],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000341544,"about_ca_system_score_gemma":0.000236387,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00107854,"about_ca_topic_score_gemma":0.001571309,"domain_scores_codex":[0.9994785,0.00008796492,0.00004841373,0.0001532521,0.0001834252,0.0000485491],"domain_scores_gemma":[0.9995752,0.0001063175,0.0001022584,0.00002066138,0.0001218133,0.00007383461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001859668,0.0001379836,0.3722948,0.0003054551,0.0002088585,0.005289697,0.0003983944,0.0002476222,0.5681933,0.00007313221,0.0004678777,0.05052321],"study_design_scores_gemma":[0.00004437912,0.001998072,0.4611692,0.00005282383,0.0003413695,0.03971142,0.0002835948,0.003632354,0.4902283,0.0001362584,0.002371681,0.00003059416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895862,0.002624385,0.006305958,0.00009043892,0.00002388687,0.00004665334,0.0003042342,0.0001888398,0.0008295514],"genre_scores_gemma":[0.9897877,0.0007588377,0.008535435,0.0001019573,0.00002519373,0.00002084399,0.000300567,0.00001948108,0.0004498534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001236397,"threshold_uncertainty_score":0.002917528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03431206959740211,"score_gpt":0.3101133103148013,"score_spread":0.2758012407173992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}