{"id":"W2163450669","doi":"10.1242/jcs.03291","title":"Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest","year":2006,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Biology; RecQ helicase; RAD51; RAD52; Helicase; Werner syndrome; Homologous recombination; Nucleoplasm; Holliday junction; Genome instability; DNA repair; Genetics; DNA replication; Bloom syndrome; Replication protein A; Minichromosome maintenance; Cell biology; Molecular biology; Gene; DNA; Control of chromosome duplication; DNA damage; DNA-binding protein; Nucleolus; Cytoplasm","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001584035,0.00009087955,0.0001386709,0.0001752511,0.00004142401,0.00004184975,0.0002407123,0.00004273925,0.000003504392],"category_scores_gemma":[0.0001670495,0.00007195508,0.00001980589,0.0004278532,0.00009898541,0.00001998625,0.00006614553,0.00008578912,0.000001466811],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004796097,"about_ca_system_score_gemma":0.0001836272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004561499,"about_ca_topic_score_gemma":0.0001091882,"domain_scores_codex":[0.9988279,0.00009448905,0.0002982122,0.000284821,0.0002601681,0.0002344479],"domain_scores_gemma":[0.9993587,0.0000147068,0.0001735997,0.0002650455,0.00008293062,0.0001050413],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004875934,0.00006888376,0.00437658,0.000005352137,0.000001077243,0.00005290734,0.00005489647,0.0001673346,0.9946207,0.00001865203,0.00002118707,0.0001248227],"study_design_scores_gemma":[0.00070572,0.0009514076,0.1357445,0.00004458669,0.000002958178,0.0001924846,0.00004752764,0.0002235958,0.8614324,0.0001113279,0.000435468,0.0001079347],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988194,0.00004198753,0.0002404583,0.0005594185,0.00002581442,0.0002388124,7.514258e-7,0.000002617618,0.00007076425],"genre_scores_gemma":[0.9952193,0.000002615729,0.004554997,0.00005774314,0.00002266162,0.00001076752,7.277362e-7,0.00000768345,0.0001235007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1331883,"threshold_uncertainty_score":0.2934243,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01379579286106917,"score_gpt":0.2619874567718886,"score_spread":0.2481916639108194,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}