{"id":"W2163450669","doi":"10.1242/jcs.03291","title":"Werner syndrome protein participates in a complex with RAD51, RAD54, RAD54B and ATR in response to ICL-induced replication arrest","year":2006,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":85,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"","keywords":"Biology; RecQ helicase; RAD51; RAD52; Helicase; Werner syndrome; Homologous recombination; Nucleoplasm; Holliday junction; Genome instability; DNA repair; Genetics; DNA replication; Bloom syndrome; Replication protein A; Minichromosome maintenance; Cell biology; Molecular biology; Gene; DNA; Control of chromosome duplication; DNA damage; DNA-binding protein; Nucleolus; Cytoplasm","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001649369,0.0005235561,0.0003128567,0.000350135,0.0002294203,0.000317033,0.0002230241,0.0004100613,0.001691128],"category_scores_gemma":[0.0002728925,0.0002058562,0.0002330256,0.0001195662,0.0002447554,0.0001928535,0.0003942835,0.0003085551,0.0005989122],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003253167,"about_ca_system_score_gemma":0.0001069443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004357369,"about_ca_topic_score_gemma":0.0005429762,"domain_scores_codex":[0.9997895,0.00004248116,0.00002070346,0.00006665865,0.00004677694,0.00003386334],"domain_scores_gemma":[0.9998821,0.00001261556,0.00003775867,0.00001437335,0.000009393401,0.00004365354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006732724,0.00001046256,0.001113462,0.00002295194,0.00001647042,0.0004177823,0.00002170039,0.00003932091,0.9975359,0.0001201295,0.00007251927,0.0005618577],"study_design_scores_gemma":[0.0000448313,0.0001355327,0.03108943,0.00001781877,0.00005796967,0.003840391,0.0000764926,0.00189244,0.957196,0.0002699602,0.005366763,0.00001233085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964131,0.00114033,0.001447903,0.000118014,0.00002163113,0.000007827512,0.000119364,0.00005779486,0.0006740704],"genre_scores_gemma":[0.9970596,0.0002155358,0.0006690262,0.00003102,0.00000470711,0.00001102909,0.0002909071,0.00001456924,0.001703506],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001691128,"threshold_uncertainty_score":0.005657375,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01379579286106917,"score_gpt":0.2619874567718886,"score_spread":0.2481916639108194,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}