{"id":"W2163453798","doi":"10.1073/pnas.072586399","title":"A role for survivin in chemoresistance of endothelial cells mediated by VEGF","year":2002,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":434,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; McMaster University; University of Toronto; Sunnybrook Health Science Centre","funders":"National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Survivin; Cancer research; Vascular endothelial growth factor; Kinase; Biology; Angiogenesis; Protein kinase B; Vascular endothelial growth factor A; Basic fibroblast growth factor; Cell biology; Growth factor; Apoptosis; Pharmacology; Signal transduction; VEGF receptors; Biochemistry; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001860476,0.000196583,0.0001730382,0.0002180528,0.0001201066,0.0004138275,0.0001661324,0.0002598364,0.0004030185],"category_scores_gemma":[0.000193406,0.00007438402,0.0001584882,0.0001197529,0.0001873137,0.0002768496,0.0001188319,0.0003290109,0.0001073929],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002508871,"about_ca_system_score_gemma":0.0001253428,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004337987,"about_ca_topic_score_gemma":0.0002906321,"domain_scores_codex":[0.9998894,0.00003118307,0.00001462642,0.00001781281,0.00002066673,0.00002630071],"domain_scores_gemma":[0.9998951,0.00002163121,0.00003057197,0.00001392355,0.00001973451,0.00001901397],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002122271,0.00005369782,0.001293916,0.00009015998,0.00001297307,0.000315374,0.00004457335,0.0001720483,0.9897956,0.001065115,0.00007648838,0.006867758],"study_design_scores_gemma":[0.00004859774,0.0008409383,0.02466036,0.00003264933,0.00007813195,0.001667526,0.0000957363,0.004211414,0.9619226,0.0004593042,0.005972394,0.0000103053],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9720685,0.01987872,0.005572346,0.0002885529,0.00004511364,0.00002353841,0.00007203044,0.00005964731,0.001991593],"genre_scores_gemma":[0.9962485,0.002496353,0.000646589,0.00004445499,0.00001122124,0.000009167752,0.00004912208,0.00000274039,0.0004919276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004337987,"threshold_uncertainty_score":0.001820326,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01801256246682297,"score_gpt":0.2586589560567482,"score_spread":0.2406463935899252,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}