{"id":"W2163464088","doi":"","title":"Synergistic activity of histone deacetylase and proteasome inhibition against pancreatic and hepatocellular cancer cell lines.","year":2011,"lang":"en","type":"article","venue":"PubMed","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Cancer Foundation; University of Alberta","funders":"","keywords":"Apoptosis; Cancer research; Pancreatic cancer; Cell culture; Bortezomib; Chemistry; Cell growth; Biology; Cancer; Molecular biology; Biochemistry; Immunology; Multiple myeloma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000250285,0.0001657693,0.0002221607,0.00005404174,0.00006410269,0.000009631547,0.0000665199,0.000144564,0.000009194371],"category_scores_gemma":[0.0001034615,0.0001637281,0.00004451139,0.00008011238,0.0002617167,0.00001142875,0.0001191604,0.0001032662,0.000001069193],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005955779,"about_ca_system_score_gemma":0.00006047357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000745568,"about_ca_topic_score_gemma":0.00015617,"domain_scores_codex":[0.9988675,0.00008973793,0.0001984064,0.0003752072,0.0001606737,0.000308478],"domain_scores_gemma":[0.9993278,0.00001322835,0.0001196045,0.000260911,0.00008674183,0.0001917496],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001923121,0.0001698342,0.002748517,0.0002592523,0.00003162153,0.00001527127,0.00009892351,0.000001351449,0.9818591,0.000008054706,0.000137743,0.01447803],"study_design_scores_gemma":[0.0006104974,0.00007575984,0.01722763,0.0000208011,0.00003280351,0.000005235553,0.00001674562,0.00008722469,0.9814044,0.00001460635,0.0003260859,0.0001781969],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946408,0.003230068,0.00008733618,0.00002431968,0.00004971495,0.0008657153,0.00004033961,0.00001251071,0.001049194],"genre_scores_gemma":[0.9969024,0.0009536276,0.0001067678,0.00002817,0.00008620063,0.001196245,0.00002443938,0.00002894493,0.0006732263],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01447911,"threshold_uncertainty_score":0.6676638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02434930710271207,"score_gpt":0.2526037392688594,"score_spread":0.2282544321661473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}