{"id":"W2163464088","doi":"","title":"Synergistic activity of histone deacetylase and proteasome inhibition against pancreatic and hepatocellular cancer cell lines.","year":2011,"lang":"en","type":"article","venue":"PubMed","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Cancer Foundation; University of Alberta","funders":"","keywords":"Apoptosis; Cancer research; Pancreatic cancer; Cell culture; Bortezomib; Chemistry; Cell growth; Biology; Cancer; Molecular biology; Biochemistry; Immunology; Multiple myeloma","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002545653,0.0003957255,0.0004842255,0.000305607,0.0001618489,0.0002305225,0.0001885844,0.0001983504,0.002331473],"category_scores_gemma":[0.0001162903,0.0001665351,0.0003526988,0.0002918733,0.0001275683,0.0002005101,0.0002165238,0.0003936379,0.0005526138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002684552,"about_ca_system_score_gemma":0.0002893001,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004255317,"about_ca_topic_score_gemma":0.001804382,"domain_scores_codex":[0.9997838,0.00004544117,0.00002119328,0.00003934365,0.00006919377,0.00004092341],"domain_scores_gemma":[0.9999108,0.00001759024,0.00001990896,0.00001277218,0.00001422329,0.00002473008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007026558,0.0001292178,0.0004682461,0.0001847068,0.00004272925,0.00005635245,0.00001303951,0.0001085129,0.99173,0.0000545188,0.0002227323,0.006287401],"study_design_scores_gemma":[0.00009491824,0.002565327,0.006332127,0.000009710001,0.00009269594,0.000525352,0.00002873386,0.0003578242,0.9849271,0.00002378759,0.005036016,0.000006603571],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9697219,0.01970791,0.003168088,0.0002909308,0.0001637071,0.0001134254,0.001181837,0.0002254786,0.005426883],"genre_scores_gemma":[0.9904367,0.003725981,0.002238403,0.0000803052,0.00003121216,0.00006958836,0.001084234,0.00001541217,0.002318173],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002331473,"threshold_uncertainty_score":0.007799506,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02434930710271207,"score_gpt":0.2526037392688594,"score_spread":0.2282544321661473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}