{"id":"W2163474660","doi":"10.1101/gad.1654808","title":"<i>PU.1</i> expression is modulated by the balance of functional sense and antisense RNAs regulated by a shared <i>cis</i>-regulatory element","year":2008,"lang":"en","type":"article","venue":"Genes & Development","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":173,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"National Cancer Institute; National Institutes of Health; Lymphoma Research Foundation","keywords":"Biology; Sense (electronics); Long non-coding RNA; Antisense RNA; Regulator; Translation (biology); RNA; Small nucleolar RNA; Cell biology; Regulation of gene expression; microRNA; Gene; Gene expression; Transcription (linguistics); Function (biology); Transcription factor; Genetics; Computational biology; Messenger RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001992287,0.0002706551,0.0002156003,0.0001956775,0.0001810262,0.0005885594,0.0001796364,0.0001972945,0.0008365135],"category_scores_gemma":[0.0003048739,0.000203402,0.0001522187,0.00009185828,0.0003887845,0.000266373,0.000242405,0.0004272867,0.0003048524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003438081,"about_ca_system_score_gemma":0.0001449225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001608244,"about_ca_topic_score_gemma":0.0002171016,"domain_scores_codex":[0.9997796,0.00003488842,0.00001273071,0.00008374,0.00004455897,0.00004447076],"domain_scores_gemma":[0.9997479,0.00006689507,0.00007406389,0.00002178382,0.00003419156,0.00005511504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004457374,0.000005529509,0.0001861299,0.000006762154,0.000001242516,0.00001195562,0.00000678954,0.00002176597,0.9987001,0.0001635527,0.000016655,0.0008350369],"study_design_scores_gemma":[0.00001280733,0.0001337773,0.006081097,0.000004786196,0.00001110749,0.0002465286,0.00002425407,0.001093837,0.9905014,0.0003227689,0.001560902,0.000006740735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933254,0.001120673,0.003146075,0.0001193305,0.00003376813,0.000007442958,0.00009517433,0.0001089315,0.002043213],"genre_scores_gemma":[0.9970129,0.0003273418,0.00151029,0.00006610907,0.00001762919,0.0000114333,0.0001461324,0.00004692025,0.0008613248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008365135,"threshold_uncertainty_score":0.002798438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01026974685720526,"score_gpt":0.2157917771627164,"score_spread":0.2055220303055112,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}