{"id":"W2163486441","doi":"10.1093/embo-reports/kve005","title":"Regulation of intracellular trafficking of the EGF receptor by Rab5 in the absence of phosphatidylinositol 3‐kinase activity","year":2001,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Endosome; Wortmannin; Endocytosis; Cell biology; Phosphatidylinositol; PI3K/AKT/mTOR pathway; Phosphoinositide 3-kinase; LY294002; Intracellular; Biology; Epidermal growth factor; Kinase; Chemistry; Signal transduction; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002474831,0.0001876551,0.0001624905,0.0001738277,0.000241247,0.0007998263,0.0002768383,0.000306939,0.0007697374],"category_scores_gemma":[0.0003163045,0.0001665883,0.0002278073,0.0001097706,0.0003204214,0.0004532985,0.0003105267,0.0004541211,0.0003777378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009374066,"about_ca_system_score_gemma":0.0003550173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001724821,"about_ca_topic_score_gemma":0.002248902,"domain_scores_codex":[0.9998166,0.00003889498,0.00002226059,0.00002212058,0.00004012421,0.00005999994],"domain_scores_gemma":[0.9998802,0.00003161273,0.00002443623,0.00002173934,0.00001794297,0.00002397937],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003938155,0.00001881939,0.0001960825,0.00003183693,0.000004895211,0.0001347755,0.00001900454,0.0001310163,0.9968177,0.0008784811,0.00005726065,0.001316287],"study_design_scores_gemma":[0.00002513372,0.00006601322,0.002538978,0.000006019076,0.00001527149,0.0002058021,0.00004970315,0.00281814,0.9923322,0.0001654354,0.001769506,0.000007819281],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957529,0.001402464,0.001071828,0.0001545024,0.00002599321,0.000005889001,0.00008521821,0.00003038088,0.001470863],"genre_scores_gemma":[0.9979299,0.0003443465,0.0004220675,0.00002981932,0.000004326809,0.000004213688,0.0001616436,0.00001078492,0.001092952],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001724821,"threshold_uncertainty_score":0.006801367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00657451038122103,"score_gpt":0.2147516589815615,"score_spread":0.2081771486003405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}