{"id":"W2163486441","doi":"10.1093/embo-reports/kve005","title":"Regulation of intracellular trafficking of the EGF receptor by Rab5 in the absence of phosphatidylinositol 3‐kinase activity","year":2001,"lang":"en","type":"article","venue":"EMBO Reports","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":50,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Endosome; Wortmannin; Endocytosis; Cell biology; Phosphatidylinositol; PI3K/AKT/mTOR pathway; Phosphoinositide 3-kinase; LY294002; Intracellular; Biology; Epidermal growth factor; Kinase; Chemistry; Signal transduction; Receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004490709,0.00008761266,0.0001466985,0.00001945329,0.00002904851,0.000003201324,0.0001124915,0.0001086469,0.00002439499],"category_scores_gemma":[0.00004555431,0.00006174989,0.0001042436,0.0001546915,0.00009376938,0.000005756891,0.00001613206,0.00007342426,1.085658e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000721455,"about_ca_system_score_gemma":0.00004229694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001035096,"about_ca_topic_score_gemma":0.00004951119,"domain_scores_codex":[0.9990599,0.00007058468,0.0003782049,0.0001812098,0.0002096521,0.0001004908],"domain_scores_gemma":[0.9990737,0.00001292627,0.0004232222,0.0004102462,0.0000640367,0.00001586768],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005738744,0.0001281117,0.04464481,0.00002928038,0.00001080095,0.000006006536,0.0002644096,0.000200054,0.9533066,0.00001573706,0.00005574717,0.001281043],"study_design_scores_gemma":[0.000138334,0.00005603517,0.0662089,0.00003925774,0.00001188536,0.00001980435,0.00007188856,0.00009677834,0.9286678,0.00003122497,0.004594848,0.00006319667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965088,0.0006093455,0.00216777,0.0000781283,0.0001160978,0.0002347349,0.000004415058,0.000002409345,0.0002783311],"genre_scores_gemma":[0.999422,0.0001153237,0.00004951404,0.00001027394,0.00003210215,0.00000517939,0.0002497908,0.000007472633,0.0001083525],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02463877,"threshold_uncertainty_score":0.2518087,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00657451038122103,"score_gpt":0.2147516589815615,"score_spread":0.2081771486003405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}