{"id":"W2163493668","doi":"10.2337/db05-0949","title":"Human Vascular Smooth Muscle Cells From Diabetic Patients Are Resistant to Induced Apoptosis Due to High Bcl-2 Expression","year":2006,"lang":"en","type":"article","venue":"Diabetes","topic":"Adipokines, Inflammation, and Metabolic Diseases","field":"Medicine","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Heart and Stroke Foundation of British Columbia and Yukon; Comunidad de Madrid; Heart and Stroke Foundation of Canada","keywords":"Apoptosis; Vascular smooth muscle; Gene knockdown; Internal medicine; Endocrinology; Fragmentation (computing); Medicine; DNA fragmentation; Artery; Downregulation and upregulation; Diabetes mellitus; Cell growth; Cancer research; Programmed cell death; Biology; Cell biology; Smooth muscle; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002432535,0.0002694576,0.0002801159,0.0004399616,0.0002006302,0.0003919048,0.0000901965,0.0002379212,0.002421417],"category_scores_gemma":[0.0004434517,0.0001621317,0.0001888239,0.0003447666,0.000132417,0.0001198956,0.0001510758,0.0004451518,0.0006835789],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008589836,"about_ca_system_score_gemma":0.0000799659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002076481,"about_ca_topic_score_gemma":0.0002433667,"domain_scores_codex":[0.9998353,0.00003037987,0.00002171561,0.00002791447,0.00005126371,0.00003349069],"domain_scores_gemma":[0.9997171,0.0000631795,0.00008267868,0.00005422216,0.00004044648,0.0000424556],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001054148,0.0001323039,0.01397646,0.00009078696,0.00004425484,0.0006495978,0.0001058324,0.00003894947,0.9730783,0.0001132385,0.0002294207,0.01048678],"study_design_scores_gemma":[0.0005227941,0.00482572,0.3061492,0.00005897824,0.0002582718,0.01858906,0.0004373081,0.001111177,0.652587,0.0004035909,0.0150199,0.0000370017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950878,0.002421696,0.0009592045,0.0001152368,0.00002195758,0.00001626696,0.0002973873,0.00003924237,0.001041291],"genre_scores_gemma":[0.9949958,0.001461685,0.0009631168,0.000118473,0.00002693115,0.00002635948,0.001345775,0.000009541292,0.001052217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002421417,"threshold_uncertainty_score":0.00810039,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008280833145944792,"score_gpt":0.2176342426473732,"score_spread":0.2093534095014284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}