{"id":"W2163498104","doi":"10.1007/s00125-005-1751-1","title":"Long-term efficacy and tolerability of add-on pioglitazone therapy to failing monotherapy compared with addition of gliclazide or metformin in patients with type 2 diabetes","year":2005,"lang":"en","type":"article","venue":"Diabetologia","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":170,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hotel Dieu Hospital","funders":"Eli Lilly and Company","keywords":"Pioglitazone; Gliclazide; Metformin; Medicine; Internal medicine; Tolerability; Type 2 diabetes; Diabetes mellitus; Endocrinology; Combination therapy; Adverse effect","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001436707,0.0002082142,0.00063382,0.0001957936,0.00002089027,0.000008059606,0.00007516922,0.00005565493,0.0001118927],"category_scores_gemma":[0.00003758751,0.0001241977,0.00002908488,0.0003425586,0.000102188,0.00009836257,0.00002102598,0.00007497784,0.000003421328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006713878,"about_ca_system_score_gemma":0.00002489116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008948979,"about_ca_topic_score_gemma":0.00004716005,"domain_scores_codex":[0.9988463,0.00004144071,0.000330529,0.0003008693,0.0002211946,0.0002596592],"domain_scores_gemma":[0.9991862,0.0001535099,0.0001435554,0.0003141059,0.0001227364,0.00007992365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.006387402,0.001796553,0.9024463,0.000083569,0.0002361319,0.000002338569,0.0002787189,0.00007717554,0.000356958,0.0000161414,0.00004529669,0.08827335],"study_design_scores_gemma":[0.01011202,0.008610117,0.9611841,0.0003141054,0.00006606942,9.905282e-8,0.00003428766,0.00004058522,0.0194175,0.00000555667,0.00007654816,0.0001389923],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981723,0.0001848625,0.00001157585,0.00008059598,0.00001891671,0.001358443,0.00002077374,0.00003109558,0.000121379],"genre_scores_gemma":[0.9977702,0.0000382914,0.001741516,0.000200614,0.00001456859,0.00006017129,0.0001212661,0.0000198895,0.00003351089],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08813436,"threshold_uncertainty_score":0.5064636,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01846969852170322,"score_gpt":0.265047966469477,"score_spread":0.2465782679477738,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}