{"id":"W2163559860","doi":"10.1681/asn.2014040326","title":"Non-Complement–Binding De Novo Donor-Specific Anti-HLA Antibodies and Kidney Allograft Survival","year":2015,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":137,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Donor specific antibodies; Medicine; De novo synthesis; Kidney transplantation; Human leukocyte antigen; Complement system; Incidence (geometry); Clinical significance; Antibody; Isoantibodies; Antigen; Kidney; Immunology; Internal medicine; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007831447,0.000233269,0.000234479,0.0004797367,0.000159865,0.0003949243,0.0001826846,0.0004459388,0.001109997],"category_scores_gemma":[0.001921584,0.0001093166,0.0002606977,0.0002417801,0.0002122228,0.0003836453,0.000249219,0.0004941572,0.0001274323],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002485207,"about_ca_system_score_gemma":0.0001662422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008435147,"about_ca_topic_score_gemma":0.0008214822,"domain_scores_codex":[0.9997221,0.00007653169,0.00002382087,0.00004815501,0.00005615986,0.00007325738],"domain_scores_gemma":[0.9975899,0.0006835038,0.001105426,0.0001217773,0.0001218288,0.0003776861],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0006202726,0.00004763791,0.9937784,0.000009103845,0.00006569587,0.0001016498,0.0000321463,0.0001729061,0.002196042,0.00002874867,0.00003139517,0.002916063],"study_design_scores_gemma":[0.000004924179,0.0001989619,0.9983428,0.00000314679,0.00002920856,0.0005163716,0.00002005182,0.0003606117,0.0004140048,0.00002501125,0.00008127869,0.000003755297],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993578,0.0003998299,0.0000802387,0.00001266004,0.000002358108,7.323088e-7,0.0000221656,0.000002203884,0.0001219916],"genre_scores_gemma":[0.9998071,0.00004738769,0.00002223114,0.000006516892,0.000004540058,4.439693e-7,0.0000368582,4.732094e-7,0.00007449814],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001109997,"threshold_uncertainty_score":0.004141748,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04149825567498186,"score_gpt":0.3218687171322306,"score_spread":0.2803704614572488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}